Ewing's sarcoma of temporal bone: case report

Primary Ewing's Sarcoma [ES] is a small round tumor, more likely to present in long bones and rarely in skull bones. ES commonly present in the second decade of life, and it is usually treated by multi?modality including surgery, chemotherapy, and radiotherapy. In this case, a 13 years old boy presented with left facial palsy and hearing loss for two weeks, treated with steroid but no improvement. MRI was done and showed left jugular foramen and cerebellopontine mass measuring 4.8[asterisk]4.4[asterisk] 3 cm. Debulking surgery of the tumor was done with multiple biopsies reported by histopathology as malignant small round cell tumor consistent with Ewing sarcoma

[Proposing a prediction model for diagnosing causes of infertility by data mining algorithms]

Introduction: About 10-15 percent of Iranian couples are infertile which is due to different causes determining particular diagnostic and treatment methods. In this study, the model presented is based on basic features and simple tests, helping physicians predict the causes of infertility

Methods: The data were taken from Sarem hospital infertility data bank by using data mining methods. First, K-means clustering was run; then, support vector machine and artificial neural network classification methods were used to predict the type of infertility, and finally, the results of two classification algorithms were compared. In addition, SPSS Clementine 12.0 was used to analyze the data and implement the algorithm in modeling part

Results: In k-means clustering, the data were divided into five clusters. In each cluster, one or more causes of infertility were observed. Then, by applying SVM and artificial neural network classification algorithms, the SVM algorithm with a polynomial kernel appeared to have the maximum accuracy

Conclusion: The findings of this study, could contribute to the understanding of the factors responsible for infertility and pave the way for future investigations. These findings can be used in future studies to develop a system for applying this model since by diagnosing the causes of infertility prior to secondary stages and before performing heavy tests, a considerable amount of time and cost will be saved, and physical burden on patient will be decreased

Central pontine myelinolysis due to rapid correction of hyponatremia induced by excessive water intake

We report a 25-year-old female with a recent diagnosis of gastric B-cell lymphoma based on imaging and pathological findings. She was discharged against medical advice after it was recommended to her, by an "alternative medicine practitioner," to restrict her diet to excessive ingestion of the "Holy water Zamzam" [natural well water in Makkah]. She presented back with altered level of awareness and severe, new-onset hyponatremia. The hyponatremia was corrected rapidly and her condition improved. Six days later, she developed the classical pyramidal and extrapyramidal features of central pontine myelinolysis, documented by MRI. The patient succumbed to her original disease 3 months later

Sporadic creutzfeldt Jacob disease

We report a 65-year-old lady who presented with rapidly progressive dementia and was found to have Creutzfeldt-Jacob disease [CJD]. On reviewing the literature, there have been only 3 case reports of CJD from Saudi Arabia. Our aim is to report this rare disease and to include it in the differential diagnosis of rapidly progressive dementia in our practice