ABSTRACT
Preeclampsia has remained one of the important obstetrical problems for which different factors have been suggested. Decrease of serum levels of albumin, total protein and phosphorous have been suggested in the pathophysiology of preeclampsia. The aim of this study was to determine serum levels of Albumin, total protein and phosphorous in normal pregnancy and preeclamptic women. In this case-control study, 100 pregnant women aged 20 to 30 years with the gestational age of 28 to 40 weeks were studied. Patients were divided into two groups: 50 women as case group [preeclampsia] and 50 women as control group [normal pregnancy]. The serum levels of Albumin, total protein and phosphorous were measured in both groups. There were no significant difference between two groups in demographic factors and mean maternal age but duration of pregnancy was significantly different in the two groups [36.29 +/- 3.2 weeks in case group and 38.19 +/- 2.5 in control group] [P<0.0001]. The mean systolic and diastolic blood pressurse and body mass index were significantly different in both groups [P<0.0001]. The mean systolic blood pressure in preeclamptic women was 149.8 +/- 13.39 and in normal group was 108.7 +/- 9.73 and the mean diastolic blood pressure in preeclamptic women was 95 +/- 8.57 and in normal group was 67.4 +/- 10.72. Body mass index was 22.84 +/- 2.07 in preeclamptic women and in normal pregnants was 21.21 +/- 2.09. There was no significant difference between the two groups in mean serum levels of albumin, total protein and phosphorous. Serum Albumin in preeclamptic women was 4.12 +/- 0.45 and in women with normal pregnancy was 4.26 +/- 0.57. Serum level of total protein was 5.95 +/- 1 and 6.03 +/- 0.92 and serum phosphorous was 3.53 +/- 0.68 and 3.35 +/- 0.82 in preeclamptics and normals respectively. There was no significant relationship serum between levels of Albumin, total protein and phosphorous and preeclampsia