ABSTRACT
Nursing education at the undergraduate level is fundamental to the training of professional nurse. In this respect, the effectiveness of nursing education programs should be evaluated. Students are the main stockholders of the educational system and head nurses as the witnesses of students' effectiveness in patient care are placed in the best positions to evaluate the educational system. The purpose of this study was to assess the achievement of educational goals from the perspectives of undergraduate nursing students and head nurses. This descriptive study was based on the approach of management based evaluation using the CIPP's model. All senior students and head nurses were selected using the census sampling method. Data was gathered using a researcher-made questionnaire that had two parts: demographic data questions and achievement to educational objectives in provision of care to patients. The data was analyzed using descriptive and inferential statistics. The majority of the students [63%] and head nurses [80%] reported the level of achievement of the educational objectives as partly desirable. Despite the higher scores from students' perspectives compared to those of head nurses, no significant difference was reported between the two groups regarding achievement of educational goals [P=0.79]. Despite the partly desirable level of achievement of educational goals, the recognition of obstacles to achievement of the goals are suggested
Subject(s)
Humans , Female , Male , Evaluation Studies as Topic , Students, Nursing , Nursing, Supervisory , Educational Measurement , GoalsABSTRACT
Matrix metalloproteinases [MMPs] plays a role in the several physiologic and pathologic events. There is some evidence indicating the involvement of MMPs in tumor invasion and inflammatory diseases. In this study we evaluated the effect of cell wall Candida albicans fraction on MMP production by the fibrosarcoma cell line using an in vitro cytotoxicity assay, sodium dodecyl sulfate-polyacrylamide, and gelatin zymography. It was an experimental study. Fraction of cell wall Candida albicans was extracted by lysis buffer and] 0, 10, 50, 100 [micro g/ml from fraction was added to human fibrosarcoma cell line in 96 well microplate and inhibitory effect on tumor cell invasion was investigated by MTT and zymography test. Our results showed that fraction of cell wall Candida albicans was found to exhibit a inhibitory effect on tumor cell line in MTT test because the viability of tumor cells was decreased versus the control groups. Also the production of metalloproteinases enzyme in presence of fraction was diminished significantly [P<0.05]. Since inhibition of MMP activity has been employed in modality therapy in diseases such as cancer, this fraction could be promised in the preparation of anti-MMP therapeutic derivatives