Association of lipoprotein lipase gene with coronary heart disease in Sudanese population

Cardiovascular disease is stabilizing in high-income countries and has continued to rise in low-to-middle-income countries. Association of lipid profile with lipoprotein lipase gene was studied in case and control subject. The family history, hypertension, diabetes mellitus, smoking and alcohol consumption were the most risk factors for early-onset of coronary heart disease [CHD]. Sudanese patients had significantly [P < 0.05] lower TC and LDL-C levels compared to controls. Allele frequency of LPL D9N, N291S and S447X carrier genotype was 4.2%, 30.7% and 7.1%, respectively. We conclude that lipoprotein lipase polymorphism was not associated with the incidence of CHD in Sudan

[Study of the antioxidant and antibacterial activity of the extracts of all parts of Capparis spinosa L. flower]

Investigation of the endemic species Capparis spinosa L. was conducted within the general framework of valorization of the medicinal plants of the Algerian and Mediterranean flora. The aim of this study is to evaluate the antioxidant activity and antibacterial activity of the crude extract of the buds, flowers and immature fruits of Capparis spinosa. Evaluation of the antioxidant activity by the test of DPPH, revealed a great antioxidant capacity especially for the methanolic extract [78,34%]. The polar fraction of the extract does not show any antibacterial activity. To the contrary, the non polar extract was found to be active against Staphylococcus aureus.

prevalence of anti - HCV virus and hepatitis B seromarkers among Egyptian rural school children and it's relation to schistosomiasis

This study was composed of 170 male students aged 11-14 years from Tamoh village, Giza governorate, Cairo. They were subjected to full history, clinical assessment, urine and stool analysis, together with HCV and HB seromarkers, using ELISA 2nd generation techniques and Abdominal ultrasonography to all studied groups. HCV seropositivity was 18 [10.58%] and there were increase in anti-HCV seropositivity among students with schistosomal hepatosplenomegaly. Anti-HCV seropositivity was not related to activity of schistosomiasis. On the other hand hepatitis B seropositivity was 8 [4.70%] and there were the number of seropositivity occurs among students with schistosomal hepatosplenomegaly only

Estimation of urinary transforming growth factor beta - 1 levelsin patients with chronic active hepatitis c virus and liver cirrhosis

This study included 21 patients with chronic active hepatitis C virus [CAM. CV] Group I and 18 patients with liver cirrhosis group II, both proved by liver biopsy. Only patient with normal serum creatinine were included in this study, and urinary creatinine was used to normalize the urinary TGF - B1 level.Twenty healthy individuals of comparable age and sex constituted the control group.This study showed that the urinary TGF-BI level was significantly higher in group 1[5.52 +/- 6.63ng/mg creatinine] than in the control group [0.185 +/- 0.15 ng.mg creatinine] ,with P value < 0.001 . As regards the Histological Activity Index [HAI], there was a significant difference between urinary level of TGF-Bi in patients with mild disease [2.8 +/- 2.4 ng/rng creatinine] and those with moderate to marked disease [11.3 +/- 8.5 ng/mg creatinine] with P value <0.05 . Urinary level of TGF-BI was also significantly higher in group II [3.45 +/- 4.18 ng/mg creatinine] than in the control group [0.185 +/- 0.15 ng/mg creatinine] with P value < 0.001. It was also higher in cirrhoticpatients with Child - B to C [9.3 +/- 4.8 ng/mg creatinine] than in those with Child - A [1.81 +/- 1.86 ng/ing creatinine] with P value < 0.05 .In conclusion, urinary TGF - B1 level may be used as a marker for hepatic fibrogenesis , and a higher urinary TGF - Bl levels correlate with more severe liver disease

Cryptococcal urethritis. a case report

A unique case of cryptoccal urethritis showing symptoms of chronic urethritis and apparently without other organ involvement is reported. The infection was successfully treated with amophotericin B and 5-fluorocytosine

Rhino-orbito-cerebral mucormycosis: report of two cases

Two acute, fatal cases of rhino-orbito-cerebral Mucormycosis are described in debilitated patients, one with renal failure and the other with uncontrolled insulin-dependent diabetes mellites. The clinical presentation was typical and the laboratory diagnosis revealed the fungal element which identified as a Rhizopus

Sonography versus peritoneal lavage in blunt abdominal trauma

Thirty cases of blunt abdominal trauma have been chosen at random in Zagazig University Hospital. Complete history taking, general and local examinations were done for every case, together with routine laboratory, selective radiological and specific investigations according to their indications. All patients underwent immediate real time sonographic examination of the abdomen by an experienced sonographer, then peritoneal lavage inclosed technique was performed and the results of both examinations were compared to the clinical course. Laparotomy was or was not performed depending on all the above examinations and investigations. The results of our study showed that, for ultrasonography alone, sensitivity was 85.7%, specificity was 88.9% and accuracy was 86.7%. For peritoneal lavage alone, sensitivity was 95.2%, specificity was 100% and accuracy was 96.7%. For clinical assessment alone, sensitivity was 69.6%, specificity was 28.6% and accuracy was 60%. For clinical and ultrasonography, sensitivity was 85.7%, specificity was 88.9% and accuracy was 86.7%. For clinical and peritoneal lavage, sensitivity was 95.2%, specificity was 100% and accuracy was 96.7%. For clinical, ultrasonography and peritoneal lavage combined, sensitivity was 95.2%, specificity was 100% and accuracy was 96.7%. Thus our results showed that peritoneal lavage is superior to ultrasonography in blunt abdominal injuries. It gives immediate results with much economy in time and activities of personnels