ABSTRACT
From the aerial parts of Lotus hebranicus L. Hochst ex Brand a total of seven flavonoid compounds were isolated and identified as: Kaempferol- 3-0- sophoroside -7-0-rhamnoside, kaempferol-3-0-sophoroside, isorhamnetin-3-0-glucoside-7-0-rhamnoside kaempferol-3,7-di-0-rhamnoside, kaempferol-7-0-rhamnoside, isorhamnetin and kaempferol. A study of toxicological and ulceroprotective effects was performed for both Lotus hebranicus L. Hochst ex Brand and Lotus corniculatus L
Subject(s)
Animals, Laboratory , Plant Extracts , Ulcer , Rats , Plant Extracts/toxicity , Mice , FlavonesABSTRACT
From the aerial parts of Retama raefam ten flavonoids were isolated and identified as saponarin, genistein 8-C-glucoside, genistein 5-O- methylether, genistein 5,4'-di-O-methylether, alpuminoisoflavone, ephedroidin, luteolin, apigenin and two new flavones, luteolin 4'-O- neohesperidoside and 5,4'-dihydroxy- [3",4''- dihydro- [3",4"-dihdroxy] -2",2"dimethylpyrano [5",6":7,8]-flavone[1]. In vitro antitumor screening of genistein-5-O-methylether and genistein-8-C-glucoside were carried out on sixty human tumor cell lines