ABSTRACT
Introduction: Breast cancer in women is second only to lung cancer with respect to cancer deaths. Early detection of this cancer is believed to improve patient survival and to prevent metastasis
Material and Method: This descriptive study was designed to evaluate the value of [99m] TC-MIBI-breast scintigraphy in differential diagnosis of breast masses. A total of 20 patients during a 12-months period [from March 2003 to March 2004] in Imam Reza Hospital evaluated. After clinical examinations and breast MIBI scan, excisional biopsy was done
Result: We studied 21 breast masses. 14 masses were malignant tumours and 7 masses were benign tumours. The mean value of MIBI uptake in malignant masses of breast was significantly greater than benign masses [P=0.05]. The sensitivity and specifity of breast scan with [99m] TC-MIBI using qualitative interpretation was 78.5% and 85.7% respectively. The sensitivity and specifity of [99m] TC-MIBI using tumour/background ratio in detection of malignancy was 92.3% and 71.4% respectively
Conclusion: In this study it was found that quantitative interpretation of [99m] TC-MIBI scintimammography considering tumour/background uptake ratio [>1.3] is highly sensitive for detection of breast cancer