ABSTRACT
The objective of this study was to investigate the effects of Transmyocardial Revascularization by Laser [TMRL] in patients of ischemic heart disease. 50 patients of ischemic heart disease NYHA class III, IV who were not suitable for other methods of revascularization like CABG, PTCA ['No Option' patients] were offered TMRL. These patients were symptomatic on maximum medical treatment. 50 patients of angina NYHA class III, IV [mean 3.44 +/- 0.50] were offered TMRL. Their angina class improved to mean 1.88 +/- 0.74 at 6 month [p=0.00585] and persisted at mean 0.96 +/- 0.77 at 2 years [p =0 0.0150]. Their ETT mean value before operation was 5.036 +/- 1.54 minutes and at 2 years mean was 6.56 +/- 1.79 minutes [p=0.8318]. Kaplan Meier symptoms free survival rate was 83.1% at 6 months [14 censored] and 77.3 at 2 years [24 censored]