ABSTRACT
The co-existence of dengue and malaria infection in an individual and the primary and secondary dengue infection during co-infection were assessed. Over 1 year, 1980 blood samples were collected from suspected cases of dengue fever and analyzed by rapid diagnostic test [RDT], enzyme-linked immunosorbent assay [ELISA] and polymerase chain reaction [PCR] methods to detect dengue infection. RDT and microscopic methods were used to detect malaria. Of the 1980 samples, only 22 [3.0%] cases were identified as dengue-malaria co-infection cases, out of which 13 were male and 9 were female. The highest number of confirmed cases were found during the hot and humid months of September and October [7 cases, 31.8%] and within the over 15 years age group. Of the cases of co-infection, dengue primary infection [21 cases, 95.5%] was significantly more common than dengue secondary infection [1 case, 4.5%] among all of the age groups. There were 12 cases of Plasmodium falciparum and 10 cases of Plasmodium vivax infection among malarial cases. A high prevalence of concurrence of dengue and malaria infection was recorded in this ecosystem. In light of the severity of co-infection and overlapping symptoms, a multidimensional diagnostic approach is suggested