ABSTRACT
The purpose of this study was to investigate the significance of the algorithm and results of transfusion transmitted infection tests in blood donor. Screening test results of the 10454 blood donor samples were evaluated the intra-assay correlations among the initial reactive and repeat screening results used in a third-generation enzyme-linked immunosorbent assays (ELISA, SD) for hepatitis B virus (HBV), hepatitis C virus (HCV). and HIV in blood samples. The initial reactive test results was positive 645 (6.2%) for HBV, 409(3.9%) for HCV, and 51(0.5%) for HIV however; repeat results was determined positive using the algorithm as follows: 462(4.4%) HBV, 341(3.3%)HCV, and 11(0.1%) HIV. Repeat screening HBV positive results was down until 4.4%, HCV 3.3% and WW 0.1% cumpairtt) with the initial results. As a result, false positive was determined I .X% for HBV, 0.6% for HCV, and 0.4% for HIV by initial reactive screening tests. The results of this study show that the implementation of the testing algorithm in blood transfusion services has a positive implication and reduces false positive rates in donors bloods.
ABSTRACT
The result of this study show that the determination rate of the first screening test of Rhesus group D antigens negativity was 1.2%, where as the confirmation analysis decreased this rate to 1.18%. Similarly, the determination rate of the Kell K-antigen positivity rate was 0.9%. where as the confirmation test decreased this rate up-to ().X5%. These result show, that it is necessary to use confirmation test in routine diagnosis of blood sub-group determination. The Rh blood group system is of considerable importance in transfusion and clinical medicine. We have determined some clinically important red cell antigens such as C,c I), E,e in 97 Rh (+) blood donors, using the monoclonal antibodies "Erithrotest-Tsoliclon", produced at the Hematology company. Russian Federation. Among these Rh (•) blood donors prevail RIR2, R1R1 .R2R2 phenotypes accounting for 36.1%, 27.X% and 11.3% respectively. Among these Rh (-) blood donors prevail rr. rr'.rr" phenotypes accounting for 74%, 16% and 4% respectively.