1.
Alexandria Journal of Hepatogastroenterology. 2006; 3 (1): 3-5
in English
| IMEMR
| ID: emr-75734
ABSTRACT
The role of IGF signaling in controlling rates of cell renewal has led to interest in the relevance of this regulatory system to both ageing and neoplasia [1, 2, 3, 4] IGFI signaling stimulates proliferation prolongs survival of cells propagated in tissue cultures [4] The insulin like growth factor 1 signaling pathway arose early in evolution, possibly as regulator of cellular proliferation in relation to nutrient availability