ABSTRACT
OBJECTIVE: To find out deranged serum lipids, a cause or effect of raised blood pressure. SETTING: Punjab Institute of Cardiology Jail Road Lahore. DESIGN: Prospective study. PATIENTS AND METHODS: A total of ninety four male subjects between 40-55 years of age were included in the study. out of these sixty three were patients of hypertension, selected from outdoors, while the remaining thirty one were taken from general population as control for comparison. Depending upon the levels of blood pressure the hypertensive subjects were divided into mild [DBP 104 mm Hg] and moderate [DBP 114 mm Hg] hypertensive groups. The serum levels of total cholesterol, were 182.31 mg/dl +/- 28.08 mg/dl in normotensive control group while these values were 205.96 mg/dl +/- 15.79 mg/dl and 261.45 mg/dl ' 57.40 mg/dl in mild and moderate hypertensive subjects. The mean serum levels of HDL cholesterol in the above three groups were 45.25 +/- 4.35 mg/dl, 42.36 +/- 2.76 mg/dl and 37.66 +/- 3.45 mg/dl. The mean serum levels of LDL cholesterol as determined by applying the formula were 102.49 +/- 29.07 mg/dl, 128.98'21.69 mg/dl and 175.32 +/- 63.72 mg/dl and man serum levels of triglycerides were 176.75 +/- 42.45 mg/dl, 175.79 +/- 58.47 mg/dl and 200.44 +/- 102.82 mg/dl in normotensive, mild and moderate hypertensive subjects respectively. CONCLUSIONS: The serum total cholesterol was increased in the hypertensive group as compared to control group. The mean serum HDL cholesterol level was significantly lower in hypertensive than in normotensive control subjects. Similarly the mean serum LDL cholesterol was higher in hypertensive as compared to normotensive subjects, while serum triglycerides showed controversial results