Role of pathology in nasopharyngeal cancer

Nasopharyngeal cancers account for 45% of all ear -nose and throat cancers at the National Institute of Oncology [cancer registry]. Carcinomas are by far the most frequent with the particularity of being tightly linked to the presence of Epstein-barr virus, sensitive to radiation therapy and lymphophilic revealed by cervical masses in 40% of the cases. A precise and reliable anatomo pathological diagnosis is therefore manasatory before intiating any treatment. Methods and The authors report the results of histopathologic techniques [routine and special stains immunohistochemistry] in the diagnosis of 143 biopsies of the rhinopharynx with a frequency of undifferentiated carcinoma of the nasopharynx [UCNT]. All biopsies of suspicion of relapse were inflammatory corresponding to mycotic inflammation in half of the cases. A special emphasis is made on the conclusive contribution of in situ hybridization on paraffin sections in positive and differential diagnosis with regard to the results described in the litterature. Therefore, in the particular context of nasopharynx cancer-frequent in our country, sensitive to radiation therapy but with possible relapses-, the authors emphasise on the specific utility, besides basic and special stainings and immunohistochemistry, of in stiu hybridization of paraffin sections, to search for the presence of Epstein-barr virus particles in tumoral cells. This technique should, indeed, be used as reliable routine technique allowing positive diagnosis of relapses and differential diagnosis in the cases of cervical masses without a known primary site and an extensive cancer of the rhinopharyngeal and sinonasal regions

Gastrites chroniques dysplasies metaplasies intestinales et carcinomes gastriques etude retrospective de 1539 cas entre 1978 et 1983

In Morocco, the gastric cancer occupies the first rank of all cancers affecting the digestive canal. The chronic gastritis remains the main precancerous lesion, which probably comes from dysplasia. The study drows the successive occurence of chronic gastritis, dysplasis and cancer. Thus to reduce the frequency of stomach cancer we propose that great attention to precancerous dyspasia in high risk population

Cancerisation des dysembryomes benins de l'ovaire: a propos de quatre observations

The reported observations concern three ovarian carcinoides in divers tissular context. One of them coexists with an adenocarcinoma and sarcoma. The last observation corresponds to a teratocarcinoma. The morphological particularities of these tumors are discussed

carcinoides gastriques: apropos de deux observations

The authors report two observations of the gastric carcinoids. The first one concerns a small fundic polyp composed of a "silent" microgastrinoma and parietal cells adenoma. The second one corresponds to a voluminous tumor of "EC cells" accompanied with carcinoid syndrome. Localization, morphology and functional activity of those tumors are discussed

Le schwannome du rein: a propos d'un cas avec revue de la litterature

One case of renal schwannoma in 32 years old woman is described. With a review of literature are analysed the anatomo-pathological features of this uncommon tumor

Mesotheliome malin peritoneal: a propos d'un cas

The authors report one case of malignant peritoneal mesothelioma in 24 year old man. Morphological particularities and histological criteria of these tumors are discussed