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Egyptian Journal of Chemistry. 1997; 40 (2): 81-91
in English | IMEMR | ID: emr-107802

ABSTRACT

The reaction of a series of erythro-2, 3-dibromo-1, 3-diaryl-1-propanones 1 a-g with 2 molar equivalents of nicotinic and isonicotinic acid hydrazides afforded 4-bromo-1-nicotinoyl and 1-isonicotinoyl-3, 5-diaryl-2-pyrazolines 2 a-g and 3 a-g, respectively. The structure of the products was confirmed by chemical and spectral tools. The mechanism of the reaction was discussed


Subject(s)
Isoniazid/chemistry , Nicotinic Acids/chemistry , Niacin , Pyrazoles
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