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Qom University of Medical Sciences Journal. 2009; 3 (2): 55-61
in Persian | IMEMR | ID: emr-93827

ABSTRACT

Pseudotumor cerebri is defined by the increase of intracranial pressure. It has different atiologies but, many of its causes are idiopathic and typically present on young obese females. Cerebrospinal fluid [CSF] analysis was normal in this case study and there was no evidence of intracranial mass, venous sinus thrombosis, or obstruction in CSF stream. In this study, we have reported a case of Pseudotumor cerebri presented 7 years after a successful kidney transplant, under treatment by Cyclosporine, Methylprednisolon and Azathioprine[AZT]. The patient was a 17-year old obese female with a body mass index of 30kg/m2 having Pseudotumor cerebri 7 years after a successful kidney transplant. Brain imaging like CT scan and MRA [Magnetic Resonance Angiography] were normal. CSF analysis was normal, but the increase in CSF pressure had been detected. Repetitive lumber punctures were performed with simultaneous Acetazolamid administration. But her headaches were treated even after the continuation of Cyclosporine and Methylprednisolon, anemia, and renal failure. For patients with kidney transplant and headaches, it is necessary to rule out Pseudotumor cerebri as a differential diagnosis. Neurotoxicity of Cyclosporine is not rare and we have to pay close attention to neurologic side effect of this drug as well. After diagnosing Pseudotumor cerebri in such patients, it is necessary to limit the progression of symptoms and avoid the decrease in patient's visual acuity


Subject(s)
Humans , Female , Pseudotumor Cerebri/drug therapy , Kidney Transplantation , Cyclosporine , Methylprednisolone , Azathioprine
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