profile of Fc-receptor and rheumatic marker after tonsillectomy

Pharyngitis in the most common site to bacterial infection of Streptococcus hemolyticus and subsequently rheumatic activity. Tonsillectomy is one of the prophylactic lines to manage rheumatic fever. The immunological differences after tonsillectomy were the aim of this work. Rheumatic marker on B-lymphocyte and Fc-receptor on blood monocytes are estimated before and after tonsillectomy. The results are compared with normal subjects and to patients with acute active disease of rheumatic fever. The rheumatic marker is significantly increased in active rheumatic patients compared to the normal control group. Meanwhile, the Fc-receptor is significantly decreased compared with normal subjects. The rheumatic marker is significantly negative correlated to the Fc-receptor in active diseased patients. The rheumatic marker after tonsillectomy is completely eradicated and closed to the value of normal control subjects. On the other hand, the Fc-receptor is significantly increased after tonsillectomy but still significantly lower than normal control subjects

Effect of serum factors regulating the pathology of rhinoscleroma

In rhinoscleroma patients, there are a complexity of reaction either pathological or immunological. Both humeral and cellular responses in relation to disease were clarified by many authors. However, the relation between humeral and cellular immune response is aim of the work. Patients sera were tested against normal monocytes and neutrophil. Fc-Y receptors, NBT and myeloperoxidase were used as markers for the studies. These markers were significantly decreased in patients with granulomatus group. On the other hand, myeloperoxidase were significantly decreased in catarral and fibrotic groups

Fungal background of asthmagenesis in Egyptian patients

To evaluate the role of fungi in the genesis of bronchial asthma in Egyptian patients, 44 asthmatics and 10 healthy normal control subjects were examined clinically and by laboratory means for routine urine, stool and blood count examination and skin prick test with extract of nine airborne fungi. Sputum culture for fungi as well as serologic examination were done consuming precipitin test with fungal extracts and immune complex detection. Skin tests for the nine fungi were also applied. These parameters indicated high degree of positivity among our asthmatic patients compared to controls, indicating considerable role of fungi in asthmagenesis, though, immune complexes were + ve in all cases indicating that type III allergic reaction has no outstanding role in asthma production. This study also showed that detection of fungus in the sputum, blood eosinophilia, positive skin reaction to fungus allergen and precipitin test, all are useful markers in diagnosis of fungal allergic bronchopulmonary disease