[Anxiety-depressive disorders among irritable bowel syndrome [IBS] patients]

Psychiatric disorders are common in Irritable Bowel Syndrome [IBS] patients. Prevalence of psychiatric disorders varies in IBS patients in different societies. To determine the prevalence of psychiatric disorders [anxiety-depression] in IBS patients in Rasht. In this cross-sectional study, 256 IBS patients were selected [using criteria of Rome III] and evaluated for psychiatric disorders. In the first phase, subjects were screened by GHQ28. In the second phase, those patients who had scores equal or more than 23 were assessed through semi-structured psychiatric interview. Socio-demographic variables including age, gender, marital status, educational level and occupation, were recorded as well. P-values less than 0.05 were considered statistically significant. Among 256 subjects 30 patients [11.7%] had no significant psychiatric symptoms and 226 subjects [83 male, 143 female] suffered from some degrees of psychiatric problems. After performing semi-structured psychiatric interview; 190 subjects [74.2%] had anxiety-depressive problems [89 patients were suffered from pure anxiety disorders, 41 patients suffered from depressive disorders and 60 patients had co-morbid anxiety-depressive disorders]. In anxiety disorders; generalized anxiety disorder [53.7%] and in depressive disorders; dysthymia [53.5%] had the most frequencies, 53.7% and 53.5% respectively. In comparisone of anxiety-depressive subjects [190 persons] and normal subjects [66 persons], there was a significant statistical differences between the gender [P=0.019], occupation [P=0.002] and intensity of IBS [P<0.001]. Although, further studies are needed to determine the relations of demographic variables and types of IBS with psychiatric disorders, it seems to more attention to the psychiatric disorders of some specific patients suffering from IBS is helpful to their treatment

Survey the frequency of depression in the last third months of pregnancy

Women are vulnerable to mood changes during pregnancy and the postpartum period. According to the current epidemiologic studies, prevalence of prenatal depression varies widely. Estimate the prevalence of depression during the third trimester of pregnancy in women who referred to alzahra hospital in rasht-winter 2007. We studied 415 randomly-selected individuals out of 900 obstetrical women in their third trimester of pregnancy, at the prenatal clinic of Alzahra hospital in Winter 2007.A Beck Depression Inventory [BDI] and a pre-determined form containing some demographic variables were applied to measure the variables of this study. 15 subjects [due to incomplete responses] were excluded from our study. Among 400 obstetrical women participated in this study, 100 women [25%] were suffered from different degrees of depression. There were significant statistical differences between depression and education [p=0.018], occupation [p=0.039] and gravidity [p=0.033]. There were no significant statistical differences between depression and socioeconomic level and age of participants. In our study, the prevalence of depression was similar to some of the other studies, also our findings about the association of depression and education, occupation and gravidity were similar to the other studies but our findings about the association of depression and socioeconomic level and age of the participants were different from the other studies. Use of structural psychiatric interview and analytical methods for determination of the prevalence of prenatal depressive disorder and its relationship with studied variables were recommended

[Normalizing SCL-90-R inventory in guilan high-school students]

SCL-90-R inventory is used for screening and assessing effect of some treatment. Its sensitivity depended on environmental factors; there are many shortcomings of its normalization in our community. To normalize SCL-90-R inventory in Guilan high-school students in the years of 2003-2004. In a cross-sectional study, 4015 subjects were selected of 153948 students using multistage cluster sampling. New version of Persian SCL-90 R, that its content validity and reliability were examined and proved [r=0.86] was used. We determined validity and reliability of new version and prepared normal tables. Data was processed with SPSS 11.5 and analyzed by appropriate statistical tests [alpha=0.05]. There were 2005 females and 2010 males that 1242 subjects were in 3rd grade and 1341 subjects were in 17 years age group. The most reliability coefficient found for depression; with test retest [r=0.93], splitting [r=0.85]; and Crunbach alpha [r=0.85]. There was a correlation between all 9 factors and with three global indices [r>0.50] and between 9 dimension of SCL-90-R and MMPI scales, that most correlation were between depression and anxiety [SCL-90-R] with neurasthenia in MMPI [r=0.59]; and compulsive-obsessive, psychosis with schizophrenia [r=0.58] we found a statistical correlation between two tests [alpha=0.05]. There was most mean and standard deviation [1.58 and 0.76 respectively] in females and in males [1.41 and 0.71 respectively] for paranoid scales. We found GSI mean and standard deviation 1.16 and 0.59 in females and 0.92 and 0.49 in males respectively with statistically significant difference [alpha= 0.05]. Our new Persian version of SCL-90-R inventory has acceptable validity and reliability: and can be used as measurement a general psychological symptoms in Guilan students