ABSTRACT
The aim of this study is to evaluate screening program using middle cerebral to umbilical artery systolic/diastolic ratio and the modified biophysical profile in the evaluation of group of patients at high risk for uteroplacental insufficiency. 50 patients were screened by modified biophysical profile and middle cerebral artery /umbilical artery systolic/diastolic ratio [20 without and 30 with intrauterine growth restriction]. The neonatal outcome was evaluated according to admission to the neonatal intensive care unit, the length of stay and the occurrence of significant neonatal complications [central nervous system complications, sepsis, acidosis, cardiomyopathy, anemia and metabolic] the incidence of significant neonatal complications was 10% and 30%, the length of stay in the neonatal intensive care unit was 3 and 3.2 +/- 1.3 days and the incidence of caesarean section due to fetal distress was 10% and 13.3% in both groups respectively. The positive predictive value of the Doppler ratio in the prediction of the neonatal outcome was 86.7%, 91.3% and the negative predictive value was 80%, 85.7 while the diagnostic accuracy was 85% 90% in groups respectively the middle cerebral artery to umbilical artery systolic/diastolic ratio is helpful in predicting the neonatal outcome especially in the growth restricted fetuses