Post surgical wound infections: a study on threats of emerging resistance

300 bacterial isolates associated with post surgical wound infections were tested in vitro for their sensitivity/resistance pattern against 20 antibacterial agents. The study indicated that the bacteria in which clinically significant resistance has now become a potential problem include Pseudomonas aeruginosa, Staphylococcus aureus, Escherichia coli, Proteus. Klebsiella, Staphylococcus epidermidis, Enterobacter and Citrobacter species. Among the tested drugs the percent resistance rate observed were tobramycin [9.75%], amikacin [10.03%], enoxacin [20.53%], ofloxacin [25.93%], ciprofloxacin [26.27%], gentamicin [29.03%], ceftrioxone [36%], aztreonam [41.07%], cefaclor [44.07%]. The conclusion from the study can be drawn that tobramycin and amikacin [aminoglycosides] and enoxacin, ciprofloxacin and ofloxacin [Fluoroquinolones] are very effective agents for treating post surgical wound infections. However resistance to these agents is rapidly increasing

Portability of water obtained through boring in Karachi

This study was carried out to detect the faecal contamination in water obtained from indigenously designed boring facilities. The presence of escherichia coli [major indicator of faecal contamination] was detected after performing the coliform test along with biochemical studies in 32 boring water samples out of 60 samples collected from various localities of Karachi city. Its presence in underground water resources definitely indicates the possible presence of water-borne pathogens