Effect of cadmium on growth in white rats

A total of 80 albino rats were divided into 4 equal groups. The first 20 rats were kept as control and the other three groups were dosed orally by 0.143, 0.561 and 2.00 mg/kg B.wt. respectively for 8 succesive weeks. The results revealed decrease in body weight in a dose dependant manner. Also the length, thickness of femur and thickness of diaphesis decreased in the same way while diameter decrease occured in the third group only. Calcium content of bone showed a decrease in the three doses levels while phosphorus revealed such effect in groups [1] and [2]. Calcium revealed a decrease in serum and increased level in urine meanwhile the phosphorus showed increase in both serum and urine