ABSTRACT
To perform an incidence and typing study of P. aeruginosa catheter associated urinary tract infection [CAUTI] in two departments of Assuit University Hospital; the department of Urology and the Intensive Care Unit [ICU]. This study was done along the period of about 4 months. It involved 150 hospitalized patients in Assiut University Hospital; half of them from the department of Urology, and the other half were from the intensive care unit [ICU]. They were divided into two groups; cases and control. The case group included 100 patients having urinary catheters for more than 3 days, with age between 10 and 63 years old. Of the case group 65 were male patients and 35 were female patients. The control group included 50 age and sex matched hospitalized non-catheterized patients; half of them were from the department of Urology, and the other half from the ICU. Urine sample were collected from both the case and control groups and examined for bacteriuria and pyuria. Then examined bacteriologically [cultural characteristics and biochemical reactions] for isolation of P. aeruginosa. The isolates were typed by pyocine typing. Catheter-associated urinary tract infection [CAUTI] represents a great proportion of nosocomial UTI. The incidence in the department of urology was significantly higher than that in the ICU. Old age, female sex, diabetes, catheterization for more than 6 days, all favors the occurrence of CAUTI. The pre-use of second, third generation cephalosporins or quinolones decreased the incidence of CAUTI while the pre-use of ampicillin and gentamicin elevated that incidence. Most of the diagnosed CAUTI cases were caused by gram negative bacilli, which were mostly single infection. Incidence of P. aeruginosa UTI was significantly higher in cases than in controls. That incidence was equal in the two studied departments. There is a high incidence of CAUTI in Assiut University Hospital. And a high level of P. aeruginosa infection. So we recommend the use of the different preventive measures
Subject(s)
Humans , Male , Female , Pseudomonas aeruginosa/etiology , Urinary Catheterization , Cross Infection , Incidence , Hospitals, University , Intensive Care UnitsABSTRACT
Objectives to analyse the prevalence of cervical chlamydia infection in women with unexplained infertility [VI] and its share among other aetiological factors; and in patients with mucopuruluent cervicitis [MPC] and its, place among other microorganisms correlated with it. Subjects and methods- the incidence of cervical chlamydia infection was studied, by collecting endocervical specimens and detecting chlamydial antigens using direct immunofluorescent antibody [IFA] test among three groups of cases: a group diagnosed to have UI [60 women], a group with MPC [20 women], and a control group [32 asymptomatic fertile women]. Cases found to have cervical chlamydia infection were treated with doxycyline and followed up after two weeks in MPC for evidence of cure and after 6 months in UI for evidence of pregnancy. Results- about 33% of women with UI were found to have cervical chlamydia infection. The corresponding precentage were 60% and 12.5% respectively in MPC and control cases. Yellow and red cervical swab tests had 83% and increased polymorphnuclear leucocytes [PMNS] in endocervical swabs had 67% positive prediction for cervical chlamydia infection in cases with MPC. Results of treating cases with UI having cervical clamydia infection were encourging and for cases with MPC results were satisfactory. Conclusions-the study indicates that cervical chlamydia infection is a common and a significant finding in cases with UI and MPC, thus it should be considered while investigating these cases. Treatment of C. trachomatis infection on presumptive grounds, based on finding positive cervical swab test and increased PMNS on gram stain, is recommended as these methods are available and found in this study to have a reasonable positive prediction