Total and placental alkaline phosphatases in pleural effusion cases

Total and placental alkaline phosphatases were estimated in serum, bronchoalveolar lavage and pleural fluid of 40 patients with different aetiologies of pleural effusion [20 malignant, 15 tuberculous and 5 transudative] in a trial to evaluate its possible diagnostic role. The results showed that serum, bronchoalveolar lavage and pleural fluid total and placental alkaline phosphatases were significantly higher [P < 0.01] in patients with exudative effusion [malignant and tuberculous] when compared with those of transudative or control group. This rise was more marked [P < 0.01] in smoker than non smoker. There was a statistically significant differences [P < 0.001] in the mean values of pleural fluid total and placental alkaline phosphatases between exudative and transudative groups with no overlap in the individual values estimation of pleural fluid alkaline phosphatase [total and placental] is helpful parameter in differentiating exudative from transudative effusion. Local and systemic alkaline phosphatases could be considered as a tissue injury marker. Smoking raises alkaline phosphatases [total and placental]

Feeding cyromazine to luhmann hens: residues in tissues and effects on some biochemical constituents

Cyromazine was fed to Lohmann hens at 0.15 ppm level supplemented the basal diet for three eeks. The build up of cyromazine residues in liver and muscles of hens up to 7th, the balance between cyromazine intake and elimination had taken place between 7 and 10 days. After cyromazine was withdrawn from the diet its residues was depleted within seven days. During the three weeks of feeding on the treated diet, the accumulated residues reduced the blood glucose and hepatic protein significantly up to two weeks, while the hepatic lipids was slightly increased on the 7th day. Also, such residues had adverse effects on the activities of alkaline phosphatase [AP] and transminases [GOT, GPT] and extend on red blood cells, white blood cells, hemoglobin content [Hb] and packed cell volume [PCV] compared with the untreated hens

case of type IV EhlerDanlos syndrome

A 45 years old female patient from Chad was admitted with recurrent attacks of epistaxis and haematemesis, producing severe iron deficiency anaemia. Investigations suggested that the bleeding had been precipitated by an uncommon disease - Type 1V Ehler-Danlos syndrome [EDS]