ABSTRACT
Statement of Problem: Oral Lichen Planus [OLP] is a common chronic inflammatory mucocutaneous disease and has different types. If they are symptomatic, they must be treated. Corticosteroid, especially in topical form, is commonly used
Purpose: The purpose of this study was to compare the therapeutic effects of two corticosteroid mouthwashes on treatment of symptomatic OLP
Materials and Method: The participants of this single-blind study were 44 symptomatic OLP patients. They included 27 females and 17 males. They were randomly divided into two groups and were given drug A [Dexamethasone 0.1%] or B [Triamcinolone acetonide 0.2%] for four weeks. Extension of lesions [mm[2]] and severity of symptoms [based on Visual Analogue Scale] were recorded before and after treatment [weeks 1, 2, 4]. Finally, SPSS 12 was used and Man-Whitney test was run to analyze the data
Results: In both groups extension of lesions and burning sensation decreased significantly during the four weeks of treatment. There was no statistically significant difference between the two groups. However, Dexamethasone 0.1% was more efficacious, in the fourth week, in reducing the size of lesions than Triamcinolone acetonide 0.2% [p = 0.02]
Conclusion: Both mouth washes were useful in diminishing pain and decreasing the size of lesions. However, Dexamethasone 0.1% was recommended for treatment of OLP because it was more efficacious than Triamcinolone acetonide 0.2%