Point-of-care utrasound use over six-month training period in Rwandan district hospitals

Introduction: Point-of-care ultrasound (POCUS) is an effective diagnostic technology in resource-limited settings. There is increasing interest in introducing ultrasound training in such environments, but few reports describing long-term follow-up and impact of a POCUS program in a resource-limited setting. We introduced a POCUS program in Rwanda, and sought to determine the number and type of ultrasounds performed, the impact of a remote quality assurance (QA) program, and the effect of POCUS on patient management. Methods: Seventeen Rwandan physicians underwent a ten-day training course in POCUS in Kigali, Rwanda. Post-course, participants tracked the ultrasounds they performed using a cloud-based storage system, recorded clinical impressions,and received periodic QA with on-site proctoring over a six-month follow-up. Remote QA to evaluate image quality was performed by five emergency ultrasound fellowshiptrained clinicians. Images were graded on a scale of 0­4. (0=no meaningful image, 2= adequate, 4= outstanding). Trainees also documented how POCUS changed clinical management. Results: Over six months, 1158 ultrasounds were performed and logged by fifteen participants at eleven regional hospitals. 590(50.9%) had matched images and interpretations available for review. Abdominal ultrasound was the most frequently performed application (19.7%), followed by liver (14.6%), obstetrics (14.5%), renal (12.4%),and spleen (11%). Across all applications, the mean score was 2.5 (SD± 0.11, 95% confidence interval, 2.39­2.54). Ultrasound result in a management change in 84% of cases. Major changes in management related to medication choice (42.4%), admission (30%), transfer to a higher level of care (28.1%), and performance of procedures (23.3%). Conclusions: During this six-month training program in Rwanda, participants used POCUS for a range of applications. The remote QA process captured 51% of ultrasounds performed. Of scans with QA, the average score was adequate to good. POCUS routinely changed clinical management. This study demonstrates the impact of POCUS in a resource-limited setting

Fecal *1-antitripsyn clearance in the differential diagnosis of steatorrhea

Efectuamos la revisión de la excreción de grasa fecal y el Clearance de alfa1-antitripsina (CLalfa1-AT) de 160 pacientes con esteatorrea en quienes el diagnóstico final se obtuvo basado en la historia clínica, examen físico, estudios radiológicos, funcionales y morfológicos. Veintedós pacientes tenían enfermedades pancreáticas y 138 tuvieron esteatorrea debido a enfermedades gastrointestinales. La combinación de esteatorrea y CL alfa1-AT normal fue una guía de utilidad para el diagnóstico de malabsorción pancreática. El CL alfa1-AT fue normal en todos nuestros pacientes con pancreatitis crónica. Sin embargo, cuando la combinación de esteatorrea y CL alfa1-AT normal estuvo presente, el diagnóstico etiológico correcto fue posible en el 23 al 50% de los casos