Influence of embryo transfer distance on pregnancy rate in ICSI cycles

To investigate the influence of transfer distance to the fundus on pregnancy rate. Retrospective single center study, including 674 consecutive cycles of ICSI done at Adam International Clinic between January 2005 and December 2005. All patients were included and data examined regarding; their age, endometrial thickness at day of HCG, endometrial pattern at day of HCG, number and quality of embryos transferred, difficulty of embryo transfer as reported by the transferor, transfer distance to the fundus as measured by trans abdominal ultrasound and if the ejection of the media inside the inner sheath of the transfer catheter was seen or not. Our data indicate that the actual distance to the fundus did not affect the pregnancy rate. Our data proves that the exact position of embryo deposition from the fundus does not influence pregnancy rate, however the use of trans-abdominal ultrasound can be of help in visualizing the catheter in the more difficult transfer and air bubbles can be documented, also ultrasound guidance adds to the confidence in the procedure by both the physician and the patient

comparative study of mixed urinary gonadotrophins regimens

To evaluate the value of using mixed protocol of urinary gonadotrophins for an ICSI/TESE program. Adam International Clinic. Normo-ovulatory women whose partners suffer from severe oligospermia or azospermia were divided into two groups: Group I: Received Fostimon/Merional and Group II received Fostimon/Menogon. All cases underwent ICSI/TESE program and followed-up till clinical pregnancy rate. There was a statistical significant difference in favor of Fostimon/Menogon protocol regarding the number of good quality embryos together with cryo good embryos. More importantly, there was statistically significant difference regarding clinical pregnancy rate in Favor of Fostimon/Menogon protocol. [49/120Vs 33/124]. Mixed protocols were also achieving better results than menogon alone or merional alone. Based on the available results achieved and according to the two cell theory, mixed gonadrotophins using Fostimon/Menogon has become the preferred protocol of ovarian simulation in our ICSI/TESE program