glucometabolic effects of oral vitamin E in non-insulin dependent diabetes

This study included 20 patients with NIDDM selected from the Diabetes clinic, Cairo University Hospitals, all of them were under diet control and oral hypoglycemic drugs, for which estimation of fasting blood glucose and serum insulin levels, postprandial blood glucose and glycosylated haemoglobin levels were done before and after 6 weeks of oral intake of vitamin E in a dose of 600 mg/day in three divided doses. The results showed statistically significant improvement in the blood glucose, serum insulin and glycosylated haemoglobin levels after the intake of vit. E, thus oral supplements of vit. E to NIDDM patients may be of value in improving glucose metabolism

Insulin response and carbohydrate tolerance among Egyptian hypertensive patients

This study was conducted on 15 hypertensive patients and 1 0 normal control subjects, in order to study the insulin response and carbohydrate tolerance among them. All the hypertesive patients stopped their anti-hypertensive drugs one week before the study. The patients and controls were matched for age sex and body mass index They were non diabetic and non smoker. The results of the study showed significantly higher both fasting and postprandial plasma glucose and serum insulin levels among the hypertensive patients than the controls and there was a significant positive correlation between plasma glucose and serum insulin levels among hypertensive patients indicating insulin resistant state. There was also significant positive correlation between both systolic and diastolic blood pressures with fasting plasma glucose and serum insulin levels

Sex difference, serum insulin and gall bladder stone formation

This work was conducted on 78 patients [39 males and 39 females] having gall bladder stone disease diagnosed by either cholecystectomy for calcular gall bladder or proved by abdominal ultrasonography. They were divided into three groups, the first group included 12 males and 10 females aged < 40 years, the second group included 12 males and 18 females aged between 40 and 60 years, the last group included 15 males and 11 females aged > 60 years. All of them were non-diabetic, and for all of them estimation of fasting blood glucose and plasma insulin levels, together with postprandial blood glucose levels were done in order to study the sex variation in serum insulin and its role in the prevalence of gall stone disease. The results showed a statistically significant higher fasting serum insulin levels in females as compared to males, especially within the age group 40 to 60 years, and this might explain the increased prevalence of gall bladder stone disease among females

Some cardiovascular risk factors in type II diabetic patients with microalbuminuria

The Study was carried on 28 patients with non insulin dependent diabetes mellitus in two groups, [each included 8 males and 6 females], one with microalbumjnuria and the other without microalbuminuria. Serum uric acid, fibrinogen, lipid profile, fasting blood glucose, body weight and duration of the diabetic state were assessed in both groups. The results showed that there was a direct and significant relationship between the duration of diabetes and the occurrence of microalbuminuria [P < 0.03]. Although there was no statistical significance between the body weight, blood pressure and microalbuminria there was significant higher total cholesterol [P < 0.04], LDL. Cholesterol [P < 0.03], atherogenic index [P < 0.02] and triglyceride levels [P< 0.05] revealing the damging effect of microalbuminuria on the cardiovascular system. Serum HDL - cholesterol, uric acid, fibrinogen and fasting blood glucose levels on the other hand were similar in both groups