ABSTRACT
The kiwi fruit is known to have dramatic antibacterial, debridement, wound contracture, and angiogenic effects. We propose that kiwifruit is an ideal candidate to enhance the process of wound healing. The present study assessed the effects of wound kiwifruit dressing on cutaneous wound healing in rat. In this experimental study, 30 male Wistar rats were randomly divided into 2 groups of control and kiwifruit group. A full-thickness dermal incision [35 mm length] was made on the right side of the paravertebral region. In the control group, one day after wound induction wounds was dressed with vaseline sterile gauze after normal saline irrigation. In the second group, the wounds were dressed with kiwifruit. Wound healing was evaluated by measuring surface area, percentage of healing, duration of healing, and wound tensile strength. Obtained results showed that the duration of wound healing in kiwi group in comparison with the control was significantly decreased. The amount of wound healing in percent was also significantly different between control and kiwi groups at days 3, 6 [p<0.001], 9 [p<0.05], 12 and 14 [p<0.01]. Comparisons of wound length between control and kiwi group per day showed that kiwi group had significantly lower wound length on day 9, 12, 14 and 16 [p<0.01, 0.001, 0.01 and 0.01, respectively] in comparisons to control group. Also, the wound tensile strength in kiwi group also was significantly greater than the control animals [p<0.01]. We concluded that our study provides some evidence to support the use of kiwi to accelerate wound healing
ABSTRACT
The extract of Coriandrum sativum L., commonly known as coriander, belonging to the Apiaceae family [Umbelliferae], is cultivated throughout the world for its nutritional value. C. sativum was shown to enhance cognitive performance and recover memory deficit. On the other hand, epilepsy induces cognitive disorders; learning and memory deficits in different animal models. Thus, the present study was undertaken to investigate the effects of C. sativum on water maze learning and memory of epileptic rats. In this experimental study, C. sativum extract was injected intraperitoneally for 7 consecutive days to experimental animals. Pilocarpine was administered [i.p.] to induce epileptic convulsions. Morris water maze [MWM] apparatus served as the behavioral model for testing spatial learning and memory. Latency to locate the platform, swimming distance and velocity were employed as variables in acquisition and probe trials, while crossing and proximity were only used in probe test. The latency and distance to reach the hidden platform increased in pilocarpine treated rats. C. sativum extract decreased the latency and distance to platform compared with control and more prominently compared with epileptic group. Pilocarpine convulsions increased the platform location latency, but C. sativum extract did not reverse this seizure induced latency increase. Conversely, C. sativum extract reversed the seizure induced proximity increase. C. sativum extract may be a useful remedy in the management of epilepsy induced learning and memory impairments
ABSTRACT
The aim of this study was to investigate whether supplementation of carbohydrate together with peptide glutamine would prevent anaerobic power decrease during repeated competitions. Twenty eight physical education male students voluntarily participated in the study. Subjects were randomly divided on a maximal power [Max power] output value basis into four groups: 1] C, group [oral ingcstion of glutamine at the dose of 0.25 gram/kg body mass in 250 ml of water], 2] M group [a single carbohydrate at a concentration of 50gram of maltodevtrin in 250 ml of water], 3] GM group [carbohydrate at a concentration of 50gram of maltodexrin + glutamine at the dose of 0.25 gram/kg body mass in 250 ml of water] and, 4] P group [just 250 ml of water and 30 gram sweetener]. Each subject performed three times Running-based Anaerobic Sprint Test [RAST] with intervals of 1 hour. Max power, Minimal power [Min power] and fatigue were calculated for each participant. There was a significant decrease in Max and Min power in P group in time series [P<0.05]. Furthermore, regarding the Max and Min power, there was significant difference between P and GM group in third bout indicating stronger influence of combination of maltodextrin and glutamine in comparison with pure consumption of glutamine and maltodextrin [P< 0.05]. It seems acute supplementation of glutamine and maltodextrin combination, 2 hours before exercise is more efficient in prevention of anaerobic power decrease than consumption of a pure carbohydrate or glutamine in repeated bouts of RAST protocol. Thus, supplementation with both carbohydrate and peptide glutamine improved the physical performance of athletes during repeated competitions. Obviously, it is necessary to do further studies