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1.
Osong Public Health and Research Perspectives ; (6): 202-202, 2019.
Article in English | WPRIM | ID: wpr-760694

ABSTRACT

In the above-mentioned article, the authors want to update the source of Figure 1 both in Figure legend and in the Reference section, which was missing the original article.

2.
Journal of Taibah University Medical Sciences. 2016; 11 (3): 211-216
in English | IMEMR | ID: emr-180220

ABSTRACT

Objectives: To study the clinical profile andmanagement of Wegener's granulomatosis [WG] with subglottic stenosis [SGS] at a tertiary teaching hospital in Eastern India


Methods: This prospective study incorporated a case series of six patients treated between 2007 and 2015 for WG with SGS. The demographic details of the patients, such as age, sex, clinical presentation, laryngeal endoscopy, imaging, laboratory tests, and medical and surgical options, are described


Results: Of the six patients, five had laryngeal symptoms, such as hoarseness or breathing difficulty, at the time of presentation. There were four female and two male patients ranging in age from 14 to 62 years. The diagnosis of all six patients was confirmed via histopathological examination. Of the six patients, one had isolated subglottic involvement, and four had a positive antineutrophilic cytoplasmic autoantibody [C-ANCA] test on presentation. All of the patients received immunosuppressant and steroid therapies at the time of diagnosis. Five patients required tracheostomy with subglottic dilatation with cold steel instruments followed by the local injection of steroids and mitomycin-C application. Four patients have shown clinical improvement


Conclusion: Although WG is a rare clinical condition, it is often confused with common ailments, which delays diagnosis, and it may involve the subglottis. The subglottis is a vital part of the laryngotracheal airway, and mild obstruction can be life threatening. The accurate and timely diagnosis of WG helps to prevent life-threatening complications, such as SGS


Subject(s)
Adult , Adolescent , Aged , Female , Humans , Male , Middle Aged , Laryngostenosis , Tertiary Care Centers , Prospective Studies , Demography
3.
Journal of Taibah University Medical Sciences. 2016; 11 (1): 82-85
in English | IMEMR | ID: emr-176319

ABSTRACT

A rare case of a unilateral single nasal polyp arising from a left frontal recess resembling an antro-choanal polyp in a 14-year-old girl is presented. A polypoidal mass completely occupying the left nasal cavity extending to the anterior nares was evident by anterior rhinoscopy. The mass was excised endoscopically, and its origin was found to be the frontal recess of the left nasal cavity, a rare occurrence in the paediatric age group


Subject(s)
Humans , Female , Adolescent , Polyps , Frontal Sinus , Adolescent , Nose , Tomography, X-Ray Computed
4.
Journal of Taibah University Medical Sciences. 2015; 10 (4): 488-491
in English | IMEMR | ID: emr-175037

ABSTRACT

Primary amyloidosis of the larynx is a rare benign disease of unknown aetiology. Isolated epiglottic involvement with amyloidosis is an extremely uncommon benign laryngeal pathology and can present with a foreign body sensation in the throat. This lesion should be kept in mind in cases with a long-standing foreign body sensation in the throat. Observation and endoscopic carbon dioxide laser excision are the main methods of treatment. Long-term follow-up is also required because of the slow progressive nature of this disease


Subject(s)
Humans , Female , Middle Aged , Epiglottis , Foreign Bodies , Larynx , Laryngoscopy , Pharynx
5.
Journal of Infection and Public Health. 2015; 8 (6): 630-633
in English | IMEMR | ID: emr-173144

ABSTRACT

Histoid Hansen's disease is a rare form of multibacillary leprosy with distinct clinical and histopathological features. This type of leprosy is a variant of lepromatous leprosy with a very high bacterial reserve. Of alarming concern is the discovery of an isolated mucosal histoid leprotic lesion inside the nasal cavity of a patient in the post-global leprosy elimination era. Our case had no history of leprosy or exposure to dapsone/multidrug therapy but had a heavy bacillary index. We are reporting this case to highlight the rarity of mucosal lesions due to histoid leprosy and involvement of the nasal cavity, as well as to create awareness and avoid misdiagnosis. This will help facilitate prompt treatment to minimize the complications and deformities of the patient and prevent its spread throughout the community

6.
Asian Pacific Journal of Tropical Biomedicine ; (12): 148-153, 2013.
Article in English | WPRIM | ID: wpr-312438

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the infection of hospital- and community-acquired "erythromycin-induced clindamycin resistant" strains or D-test positives of clinical isolates of Staphylococcus aureus (S. aureus) (with and without methicillin resistance) in a hospital.</p><p><b>METHODS</b>Strains of S. aureus isolated from clinical specimens were subjected to D-test and antibiotic profiling.</p><p><b>RESULTS</b>Of the total 278 isolates, 140 (50.35%) were D-test positives and the rest were D-test negatives. Further, of 140 (100%) positives, 87 (62.14%) and 53 (37.85%) strains were from males and females, respectively. Of 140 (100%) positives, 117 (83.57%) were methicillin resistant S. aureus and 23 (16.42%) were methicillin sensitive S. aureus; of 140 strains, 103 (73.57%) strains from persons with and 37 (26.42%) were without related infections; of 140 strains, 91 (65%) and 49 (35%) were from hospital- and community-acquired samples, respectively. In 140 strains, 118 (84.28%) with comorbidities and 22 (15.71%) without comorbidities cases were recorded; similarly, persons with prior antibiotic uses contributed 108 (77.14%) and without 32 (22.85%) positive strains. These binary data of surveillance were analyzed by a univariate analysis. It was evident that the prior antibiotic uses and comorbidities due to other ailments were the determinative factors in D-test positivity, corroborated by low P values, P=0.001 1 and 0.002 4, respectively. All isolates (278) were resistant to 17 antibiotics of nine groups, in varying degrees; the minimum of 28% resistance for vancomycin and the maximum of 97% resistance for gentamicin were recorded. Further, of 278 strains, only 42 (15.1%) strains were resistant constitutively to both antibiotics, erythromycin resistant and clindamycin resistant, while 45 (16.2%) strains were constitutively sensitive to both antibiotics (erythromycin sensitive and clindamycin sensitive). Further, of the rest 191 (68.7%) strains were with erythromycin resistant and clindamycin resistant, of which only 140 (50.35%) strains were D-test positives, while the rest 51 (18.34%) strains were D-test negatives.</p><p><b>CONCLUSIONS</b>In view of high prevalence of D-test positive S. aureus strains, and equally high prevalence of multidrug resistant strains both in community and hospital sectors, undertaking of D-test may be routinely conducted for suppurative infections.</p>


Subject(s)
Female , Humans , Male , Anti-Bacterial Agents , Pharmacology , Clindamycin , Pharmacology , Community-Acquired Infections , Epidemiology , Microbiology , Cross Infection , Epidemiology , Microbiology , Drug Resistance, Bacterial , Erythromycin , Pharmacology , Hospitals, Teaching , India , Epidemiology , Methicillin-Resistant Staphylococcus aureus , Staphylococcal Infections , Epidemiology , Microbiology , Staphylococcus aureus
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