ABSTRACT
Peripheral Giant Cell Granuloma or so called “Giant cell epulis” is the most common oral giant cell lesion.It usually presents as a purplish-red soft tissue nodule consisting of multinucleated giant cells in a background of mononuclear stromal cells and extravasated red blood cells. This lesion probably does not represent a true neoplasm but it may be a reactive in nature which is believed to be stimulated by local irritation or trauma, but the cause is not known with certainty. A case of peripheral giant cell granuloma arising at the left maxillary premolar region in a 18 year old boy is being reported here. The lesion was completely excised upto the periosteum level; there was no residual or recurrence of swelling or bony defect apparent in the area of biopsy after a follow-up period of 1 year.