ABSTRACT
Previous studies have demonstrated and increase in bone mass and density with use of alendronate sodium. This agent acts as an inhibitor of osteoclast activity and is thought to result in more net osteoblastic activity. The objective of this study was to determine the effects of locally applied alendronate on guided bone regeneration around dental implants. The study was conducted on seven adult dogs, where bilateral extraction of their mandibular first premolar was performed after the reflection of gingival mucoperiosteal flap and immediate HR-implants [MTM-system] were placed on both sides. Bisphosphonate gel was applied on the right side only around and coating the implant [experimental group], while in the left side the implant was placed without adding the gel [control group]. The animals were sacrificed at one and two months postoperatively. Specimens were evaluated radiographically, histologically and histochemically. Radiographic results showed an increase in radiographic bone density at 1 and 2 months in experimental group. Histologic results revealed early osteoblastic activity; coarse bundles of collagen fibers covering and growing between alendronate gel at 1 month in experimental group. At 2 months, new bone formation and dense mature lamellar bone were observed directed towards implant. Histochemically, results confirmed the histological findings. In conclusion, this study implies that topical delivery of alendronate at surgery increases early bone formation around formation around immediate dental implants
ABSTRACT
This study was conducted to evaluate clinically and radiographically the use of acellular dermal matrix allograft [alloderm] in combination with PLA -PGA [Fisiograft] in management of osseous defects around seven immediate dental implants in the maxillary anterior region. Patients were seeking treatment with implants for their hopeless maxillary teeth. Preoperative study casts were constructed. Periapical radiographs and orthopantomographs were taken. Phase-I surgery, including plaque control measures, scaling and root planning, was performed for each patient. The selected teeth were extracted atraumatically after the reflection of full-thickness flaps buccally and palatally. One -piece HR implants were placed immediately into the sockets after drilling 3 to 4 mm beyond the root apex. Fisiograft in powder form was applied in the osseous defects around the implants and the alloderm membranes were placed over the graft material and secured under the flaps and the wounds were sutured. The implants were immediately restored with provisional crowns free from occlusion. Patients were evaluated both clinically at 1, 3, and 6 months after loading and radiographically at 1 and 6 months after implant placement. Results showed that the materials used fulfilled the aims that they were used for. The Fisiograft functioned well as space maker and scaffolding material. The alloderm performed well as a membrane to be used in association with immediate implants as well as its potentiality to increase the width of keratinized gingiva which is an important feature for implant esthetics
ABSTRACT
Aim: The aim of this study was to evaluate whether the locking plates when used on the superior border of the mandible were as efficient as superior border osteosynthesis using non compression conventional mini plates in the fixation of mandibular angle fractures in edentulous posterior segments
Material and methods: 10 patients with non comminuted mandibular angle fractures with edentulous posterior segment were included in this study. The patients were divided equally into 2 groups. In group I patients were treated with 2mm. conventional minipales without IMF. While in group II 2 mm-locking plate system was used without IMF. Patients were examined clinically and radiographically pre-operatively as well as post-operatively at one week, one month and 3 month intervals
Results: In both groups restoring and securing normal occlusion was achieved easily. All the fracture sites have healed uneventfully except for one case in Group I, where local infection was treated successfully by antibiotics and incision and drainage. No complications, that necessitated early plate removal were reported for any of the two groups. There was no clinical evidence of nerve damage or wound dehiscence
Conclusion: A single locking plate applied superiorly along the external oblique ridge provided adequate rigidity when used for fixing noncomminuted mandibular angle fractures in partially edentulous patients, with no superiority of the locking plates over the conventional miniplates
ABSTRACT
Fifty cardiac patients suffering namely from angina pectoris and undergoing minor dental sur-geries including surgical removal of badly destructed lower mandibular teeth [half of the patients n = 25], impacted mandibular wisdoms [fifteen patients n = 15], while the remaining ten patients underwent excision of gingival overgrowth or incision of abscesses in their mandibular labial, buccal or lingual mucosa. The patients were divided into 2 groups of equal number [n = 25]. Group A received mepicaine-L as local analgesic agent and acted as a control group. Group B received me-peridine as local analgesic drug [study group]. Both groups underwent surgical procedures under the same technique via inferior alveolar and lingual nerves block by the direct method:and supplemented with infiltration of long buccal nerve when needed. Evaluation of the patients were done by: observing the vital signs [pulse rate, blood pressure and respiratory rate] before injection and after , 15 minutes from surgery. Assessment of analgesic effect by measuring the onset, degree and duration of analgesia. Incidence of complications, and finally the systemic sedative effects. Results showed that the local analgesic effects of both drugs were almost the same, and that me-peridine is specially recommended in critically compromised patients [cardiac] and that it gets an advantage over the local analgesics as accidental intravenous injection of it is not a problem to worry about because the general analgesic and sedative effects of meperidine [pethidine] may be beneficial to the patient