ABSTRACT
This work studied the mechanism of the action of fish oil rich in eicosapentaenoic acid [EPA] and docasahexaenoic acid [DHA] [omega-3 fatty acid] on postmenopausal symptoms and bone resorption in intact and ovariectomized [ovx] female rats. The effects of dietary supplementation of fish oil [omega-3 fatty acid] for eight weeks on hypothalamic-pituitary-gonadal axis, bone formation markers, bone resorption markers and bone mineral metabolism were tested. It was concluded that the resulted data could be the protective mechanisms of fish oil against postmenopausal osteoporosis. These mechanisms based on promote positive calcium balance, increase osteoblastic bone formation and decreased bone resorption
Subject(s)
Animals, Laboratory , Female , Fish Oils , Fatty Acids, Omega-3 , Phosphorus , Parathyroid Hormone , Treatment Outcome , RatsABSTRACT
The present study suggests that sun exposure has no direct effect as a cause of lichen planus, rather, it may trigger a chain of immunological reactions ending with the appearance of lichen planus