comparative study between the Montessori curriculum and the developed curriculum of the Egyptian Ministry ofEducation in the capabilities of creative thinking for kindergarten children

Problem: The research studies the comparison in the Capabilities of Creative Thinking of kindergarteners between Montessori's curriculum and the Developed Curriculum of the Egyptian Ministry of Education. The Research's Question was there significant differences in the average total scores in the Capabilities of Creative Thinking between kindergarteners who use the Montessori curriculum and kindergarteners who use the Curriculum of the Egyptian Ministry of Education?

Aim:The research aims to measure the creative capabilities of kindergarteners by using both the Montessori curriculum and the Curriculum of the Egyptian Ministry of Education and to make a comparison between the Montessori curriculum and the Curriculum of the Egyptian Ministry of Education in the Capabilities of Creative Thinking

Methodology: The researcher depended on the Comparative Approach by using two groups, a group of kindergarteners under Montessori's, and another that uses the Curriculum of the Egyptian Ministry of Education

Community: The researcher relayed on 60 children divided into two groups of 30 students each. One group in Montessori's classrooms; and the other in the curriculum of the Egyptian Ministry of Education classrooms

Tools: Goodenough-Harris Draw-a-Person test, to measure the intelligence level, and The Creative Thinking Test by E. Paul Torrance

Statistical Methods: Will be used the value of T-test to find the difference of the averages between the two groups

Results: There are significant statistical differences in the Capabilities of Creative Thinking between kindergarteners in Montessori's curriculum and the Developed Curriculum of the Egyptian Ministry of Education

Screening of natural products for therapeutic activity against solid tumors.

Most of the currently used cancer therapeutics are natural products. These agents were generally discovered based on their toxicity to tumour cells using various bioassays. Although the exact mechanisms of action of the most commonly used cancer therapeutics such as anthracyclins, podophyllotoxins and camptothecin are incompletely understood, it is becoming increasingly clear that these agents often show complex modes of action at the cellular level, interacting with numerous targets. Such complex modes of action may be the very reason for clinical efficacy. For discovering new cytotoxic anticancer drugs sophisticated screening methods were used. The principles of such screening projects conducted, using collections of purified natural products or extracts from plants have been described. By performing simple but robust pre-screening tests such as the brine shrimp assay, bioactive extracts can be identified. Extracts (65) prepared from a collection of Egyptian plants were identified that showed cytotoxity on HepG2 cells. Interestingly, 22 (33%) of these raw extracts, induced > 2-fold induction of caspase-cleavage activity in a colon carcinoma cell line, consistent with induction of apoptosis. Only a fraction of the diversity of the biosphere has been tested for biological activity and novel cancer therapeutics remains to be discovered.