ABSTRACT
The association between overt hypothyroidism and altered lipid profile is well known, whereas the significance of dyslipidemia in subclinical hypothyroidism [SCH] is still a matter of debate. The aim of the present study was to evaluate the lipid profile in patients with SCH in comparison to controls. Serum lipid parameters of 34 patients with SCH and 34 age- and sex-matched healthy controls were evaluated in our study. TC [198.88 +/- 42.90 vs 171.40 +/- 26.24 mg/dl, P < 0.01] and LDL-C concentrations [129.04 +/- 35.44 vs 106.71 +/- 26.21 mg/dl, P < 0.01] as well as ratio of LDL-C/HDL-C [3.51 +/- 1.46 vs 2.81 +/- 0.80, P < 0.05] were significantly higher in the patients in comparison to the controls, whereas HDL-C and TC/HDL-C ratio remained unaltered. TG concentrations were higher in the patients but this difference did not reach statistical significance [0.063]. Correlation analyses revealed a significant correlation of TSH with TC, LDL-C and LDL-C/HDL-C ratio [r=0.351, r=0.345, r=0.340, respectively, P < 0.01] and a borderline correlation with TG [p=0.051]. Our findings showed that SCH is associated with some lipid abnormalities suggesting higher risk of cardiovascular disease in these patients which seems to weigh in favor of treatment of patients with SCH
ABSTRACT
Background: Diabetes is considered as one of the most important health issues in 3rd millenary that the number of the patients is increasing. Self-care has been known as one of the most effective method for The prevention and control of diabetes complications. This research was performed to assess the selfcaring grades in diabetic patients who come to Qom diabetes community in 1391.
Materials and Methods: this cross-sectional descriptive and analytic study was conducted on 251 diabetic patients referring to the Qom diabetes community and was selected randomly. Demographic and information record checklist and also standard SDSCA questionnaire were used to collect data. Obtained information was analyzed through SPSS software 18 and p value lower than 0.05 was considered as significant level.
Results: Results showed a proportion of 32.99% have never performed any self-caring activity and only 7.97% of them followed these every day. The mean values of FBS and HbA1c were 157.74 mg/dl and 7.74 mg/dl, respectively and also selfcaring score was 46.53. There was observed a significant reverse association between FBS and HbA1c values.
Conclusion: Self-caring is substantially unacceptable in diabetic patients who are under covered of Qom diabetes community and they don't perform some self-caring actions like diary regime, appropriate exercise, control of blood glucose, foot caring and also taking medicine or insulin injection completely and regular. For this reason, these patients had inappropriate values of FBS and HbA1c
ABSTRACT
Cardiovascular diseases are among the most common causes of death and disability in patients with type 2 diabetes. According to some studies, Vitamin D deficiency is associated with risk of type 2 diabetes and cardiovascular diseases. The aim of this study was to compare the serum level of Vitamin D between diabetic patients with coronary artery diseases and control group. In this case-control study, patients with diabetes referred to Shahid Beheshti Hospital of Qom for coronary angiography, were divided into two groups of positive angiography [case group] and negative angiography [control group]. In this study, stenosis of the lumen of at least one coronary artery more than 50% was considered as positive angiography and suffering from coronary artery disease, and stenosis lower than 50% was considered as negative angiography. Personal characteristics, biographical information, consisting of age, gender, history of hypertension, hyperlipidemia, smoking, history of coronary artery disease, and family history were recorded using a questionnaire. Venous blood samples of the patients were taken to measure the serum level of 25-hydroxy Vitamin D, and the two groups were compared in terms of Vitamin D level. The mean serum level of 25-hydroxy Vitamin D was 35.09 +/- 26.41ng/ml. Also, there was no significant difference between case and control groups. The level was 35.67 +/- 29.58ng/ml in the case group and 34.50 +/- 23.30ng/ml in control group. The level of Vitamin D in patients with cardiac disease had no significant difference. The results of this study indicated that there was no relationship between serum level of 25-hydroxy Vitamin D in type 2 diabetic patients and stenosis of coronary arteries