ABSTRACT
Effect of treatment with hexane, ethanol and water extracts of Egyptian clover flowers [ECF] Trifolium alexandrinum on streptozotocine induced diabetic albino rats was studied.By the end of the experiment control rats gained 38.91 % of their original body mass. In the other hand diabetic group lost 30.82 % while the ECF extracts treated diabetic groups showed no significant change in their body mass. Streptozotocine induced diabetes produced remarkable effects on rats kidney function. Serum total protein, albumen, urea, uric acid and creatinine were significantly increased. In the other" hand, serum sodium and chloride were significantly decreased while potassium and magnesium was not significantly changed. Daily urine volume and consequently renal excretion of albumen, urea, uric acid, creatinine, sodium and chloride were significantly increased. Remarkable improvement of renal function of diabetic rats was observed after treating with .ECF extracts especially the group treated with water extract