Bioactivity studies of the aqueous extract of Ocimum sanctum linn. [Labiateae]

Hot water extract of Ocimum sanctum L. [Labiateae] showed bioactivity against brine shrimp lethality bioassay. The LC50 value was found l35micro g/ml and the ED50 value was calculated l3.5micro g/ml. The extract was ineffective on wheat rootlet growth inhibition bioassay. O. sanctum showed dose related antimicrobial activity against some clinical bacterial isolates Escherichia coli, Staphylococcus aureus and Salmonella typhi but failed to exhibit activity against Pseudomonas aeruginosa and Klebsiella pneumoniae