[Do biologic parameters [prothrombin time platelets], allow to assess the degree of fibrosis in liver diseases?]

The goal of our study is to assess the performance of a score combining 3 serological parameters [PT, platelets and transminases] in predictive hepatic fibrosis. The study involved 54 patients, 29 of which resulted in distributing them according to the score of Metavir into 2 groups: Group A with mild fibrosis [F1,F2] and group B with severe fibrosis [F3,F4]. PT, platelets and transminase values in serum were assessed for all patients. The total score of the 3 biological parameters combined, was significantly more enlabled in the severe fibrosis group than in the mild fibrosis group [P=0,01] but it was not of much importance in 30% of cases as it did not allow to classify the patients with certainty in group A or in group B. This score does not seem to grant exemption from needle liver biopsy, but it can be improved by the association of other direct markers of fibrosis

[Gastritis cystica polyposa: report of 7 cases and literature review]

Gastritis cystica polyposa [GCP] is a rare inflammatory disease of the gastric remnant that usually develops after partial gastrectomy. It is defined by the presence of polyps on anastomotic gastric mucosa and at histopathobogicat examination, by the presence of mucosal and submucosal cysts with foveolar hyperplasia. The disease is characterized by the frequency of gastro-intestinal bleeding and possibility of carcinomatous association. We report seven cases of GCP collected over 5 years [1994-1999]. Diagnosis was made 9 to 45 years after partial gastrectomy and Finsterer. The patients were 52 to 72 years old. Revealing symptoms were cardiac failure, cardiac ischemia, melena, severe anemia and epigastric pain. For one patient, GCP was discovered casually. Endoscopic examination showed in all patients the presence of several polyps sized between 3 to 15 mm on the perianastomotic gastric remnant. Histology examination of the polyps showed microscopic a features of GCP in all cases. in one patient, there was a mild it glandular atrophy with extensive intestinal metaplasia and mild dysplasia. Helicobacter pylori was present only in this case