ABSTRACT
To investigate the outcomes of macrosomia and compare the risk factors associated with neonatal and maternal complications between mothers with gestational diabetes [GDM] and Non-GDM mothers, and determine whether it is important to screen for GDM before birth. We sampled the venous blood of the mothers of 120 macrosomic neonates in the first 24 hours after delivery, and assessed glycohemoglobin [HbA1c] levels. A diagnosis of GDM was based on a HbA1c > 5.9%. Twenty-three [19%] mothers had an HgbA1c > 5.9%. Maternal and neonatal complications were not significantly different in undiagnosed GDM and non-GDM women. Except for the mother's age, parity, and BMI, other risk factors for the development of GDM didn't differ significantly between the two groups. The frequency of neonatal and maternal complications associated with the birth of macrosomic neonates are not significantly different between GDM and non-GDM mothers. Hence, the universal screening of pregnant women for GDM is not recommended
ABSTRACT
To evaluate the state of iodine uptake and frequency of goiter in a previously endemic population after use of iodine salt for ten years. In an area in south of Iran following examination of randomly selected 1504, 8-10 year school children, 102 cases with grade 2 or larger goiter were found. One hundred normal cases regarding thyroid examination were also selected as controls. From all 202 children, random urine specimen was assayed for iodine as an indicator of iodide intake. Frequency of goiter grade 2 or larger was 6.8%. Median levels of urinary iodine in goiterous children and controls were 20.00 micro g/dL and 24.50 micro g/dL respectively. Values more than 10 micro g/dL indicate sufficient intake. Frequency of iodine deficiency in patients with goiter was 14.0% vs. 12.7% in control group. There was no statistically significant difference between the two groups [P value=0.748]. Iodized salt has been effective to provide acceptable iodide intake but other causes are supposed to be responsible as etiologic factors for persistence of endemic goiter