ABSTRACT
Surgical removal of impacted third molars is amongst the most common surgical procedures performed by oral and maxillofacial surgeons. Every year many articles are published in different journals regarding different aspects in such surgeries. It is necessary to translate such vast amounts of data into simple and easily comprehensible sentences for the students of dentistry and oral surgery. This article is a modest and simple review of the recent literature and presents a number of tips, recommendations, and cautions intended to improve the quality of clinical practice in third molar surgery
ABSTRACT
Introduction: Osteon is an alloplastic material containing 70% hydroxyapatite and 30% beta-TCP. Calcitonin, a hormone produced by the thyroid gland, not only prevents bone resorption by reducing both the number and the activity of osteoclasts, but also stimulates bone formation. Considering the favorable effects of calcitonin on bone formation, we hypothesized that the addition of calcitonin to Osteon would result in better bone regeneration. Materials and Methods: To test this hypothesis, full-thickness bone defects were created bilaterally in the femoral condyles of 12 New Zealand white rabbits. The defect was filled with Osteon on one side [the control group]; while on the other side, the defect was filled with a combination of Osteon and calcitonin [the experimental group]. Result: These findings showed that the number of osteoblasts and the degree of calcification in the experimental group were significantly higher than the control group [P = 0.05]. Conclusion: On the basis of these findings, it is plausible to suggest that the addition of calcitonin to hydroxyapatite and beta-TCP as alloplastic materials could contribute to a greater degree of osteogenesis
ABSTRACT
Surgical repair of cleft palate with a bony bridge may offer some distinct advantages including a lower rate of fistula formation. The goal of this study was to evaluate the feasibility of surgically inducing cleft palate and reconstruction of the cleft with the use of bone morphogenetic protein-2 [BMP-2] in sheep. In the control group [two sheep], the cleft palate was repaired with standard von Langenbeck technique. In the study group [two sheep], the cleft was repaired with the same technique with the exception that a BMP-2 gel was placed between the two oral and nasal layers. Two months after cleft repair surgery, animals were sacrificed and the cleft sites were evaluated histologically with the use of light microscopy. The results showed that surgically inducing cleft palate and repairing the cleft is feasible in sheep. Microscopic evaluation showed no bone formation in control group and minor bone formation in the study group. To determine whether BMP-2 is a useful adjunct to standard cleft palate repair techniques, an animal study with larger population is required