study of lymphadenopathy in children

Ninety-three lymph node biopsies were taken from 93 children with lymphadenopathy in whom surgical biopsy was indicated. Forty-eight cases were due to infective causes including tuberculosis, toxoplasmosis, dermatrophic and viral. Twenty-three cases were caused by malignant neoplasia. Eighteen cases showed reactive hyperplasia and collagen disease was detected in four cases. Biopsy taking for a final diagnosis should be done in all cases of generalized and localized lymphadenopathy, if it is not reached by conventional methods, especially when the nodes persist and have no obvious cause