Relationship between the residual in Tianhui medical slips and in / 中国针灸

Except the complete literature of , Tianhui medical slips unearthed in Chengdu also include a part of literature document on meridian, which was seriously damaged. Both of them were found in the same box together with . The title of the document chapter was not found in the residual medical slips. By investigated the textual content, it was discovered that such medical slips were different from the Mawangdui silk books, i.e. and , of Zhangjiashan bamboo slips of Han Dynasty, as well as in Tianhui medical slips. But, the sentences in description are similar to the sentences of in (), therefore, this residual slips was named as () by the collator. In the paper, by the comparison of this residual slip chapter with the unearthed literature document on meridian as well as in , the origin and evolution of meridian theory of traditional Chinese medicine in the Qin and Han dynasties were explained. By taking it as an example, the construction process of classical theory of traditional Chinese medicine was explored.

Identification of Chinese character "in and " in / 中国针灸

In order to identify the differences between " in () and " in (), the edition of Ninna-ji, Japan, the author analyzed all " and "of the extant , its annotation books, its handed-down books and its collated books during the past dynasties. " and " are similar in Chinese character pattern. The authors had also analyzed the evolution factors of Chinese character patterns in detail, which induced the misunderstanding of " as ". Hence, the phonology and Chinese exegetics were adopted in analysis. " and "()" were completely same in ancient pronunciation. In compliance with the theory as seeking for the connotation from the pronunciation, " was explained as "()", meaning cleft needling or point needling. Additionally, the academic significance of " was explored. It was believed that it was the specific recognition stage from the vessel to the point regarding the sites of acupuncture and moxibustion in terms of the differences in needling techniques, i.e. vessel needling, muscle needling or tendon needling. It is concluded that " resulted from the misunderstanding of " in the books of different dynasties, hence, the mistakes in the explanation and annotation of " since the Northern Song Dynasty have been clarified.

Acupuncture techniques recorded in the Tianhui bamboo slips of medicine in the tomb of the Han Dynasty / 中国针灸

was nominated after the collection of the bamboo slips of medicine unearthed from the tomb of the Han Dynasty in Tiahui county, Chengdu of Sichuan Province. It is the special chapter on the therapeuticmethods of acupuncture, providing the valuable new historical evidences for the study on the inheritance and evolution of acupuncture in TCM. In the paper, using the cross-proof method among the unearthed literature, the inherited literatures and the unearthed relics, the ancient acupuncture techniques at the early Western Han Dynasty were explored. It was discovered that the manipulations of the different needling techniques, such as pulse needling and intermuscular needling, as well as the forms of the needling tools provided the evidences to the Nine Needles recorded in () and the archaeological discovery. There were many acupuncture prescriptions, reflecting the needling methods recorded in () and () as well as needling chart, the stone portrait of the Han Dynasty. The close combination between the acupuncture needling techniques and the pulse diagnosis indicates the theoretic essence of the meridian medicine at the ancient time.

Interpreting the Methods for Blending Decoctions to Treat 60 Ailments in Tianhui bamboo slip medical manuscripts / 中国中药杂志

Among the medical texts excavated in 2012-2013 from the Han Dynasty tomb at Tianhui township in Sichuan province, we found a collection on the treatment of 60 ailments. Under each ailment, we found one or more formulas, for a total of 106 formulas. The authors of this paper compiled and analyzed these texts based on the original bamboo slips and named this collection with the title Methods for Blending Decoctions to Treat 60 Ailments because the content was focused on blending and making medicinal formulas, and also due to the historical connections with the texts the Record of the Court Scribe, "Biography of Bian Que and Cang Gong". For these reasons, this title was determined, where "blending decoctions" mean "blending and harmonizing medicines optimally in preparation for decocting". The Tianhui texts preserve ancient forms of medicinal formulas, including some once believed to be lost, such as "grain decoctions", "fermented alcohol decoctions", and "fiery decoctions". Based on the historical evidence, we can now ascertain that this text is the "Blending Formulas and Making Decoctions" mentioned in the Record of the Court Scribe written by Cang Gong. Moreover, the medical texts, Canon Formulas in Decoction Form (from the book of Han Dynasty) and the Imperial Pharmacy Formulas to Benefit the People in Song Dynasty are both of this genre of medical literature. The Tianhui text is therefore a representative of this genre of literature in the Western and eastern Han, acting as a key link between early medical formula books and later formula books.

Comparative study on transport devices relieving pressure injury during long-distance referral of critical patients / 医疗卫生装备

Objective To investigate the effect of long-distance referral on pressure injury in critically ill patients,and to explore the effectiveness of transport devices in reducing the risk of skin pressure injury.Methods Totally 97 patients hospitalized from July 2015 to June 2016 were enrolled as the subjects after long-distance referral,of whom,52 ones from July to December 2015 were selected into a control group applying common sponge mattress and the remained 45 ones from January to June 2016 were chosen into an experimental group using inflatable mattress during the referral.The two groups were compared after the referral on the incidence rates of pressure injury and its early symptoms.Results The experimental group had the incidence rate of early symptoms being 8.9％,which was statistically different from that (42.3％) in the control group (P=0.00,x2=13.73).The incidence rate of pressure injury was 6.7％ in the experimental group,which was significantly lower than that (34.6％) in the control group (P=0.000,Z=-7.849).Conclusion There is high risk for pressure injury during long-distance referral of critical patients,and proper transport device has to be involved in to lower the risk effectively.

Comparative study on transport devices relieving pressure injury during long-distance referral of critical patients / 医疗卫生装备

Objective To investigate the effect of long-distance referral on pressure injury in critically ill patients,and to explore the effectiveness of transport devices in reducing the risk of skin pressure injury.Methods Totally 97 patients hospitalized from July 2015 to June 2016 were enrolled as the subjects after long-distance referral,of whom,52 ones from July to December 2015 were selected into a control group applying common sponge mattress and the remained 45 ones from January to June 2016 were chosen into an experimental group using inflatable mattress during the referral.The two groups were compared after the referral on the incidence rates of pressure injury and its early symptoms.Results The experimental group had the incidence rate of early symptoms being 8.9％,which was statistically different from that (42.3％) in the control group (P=0.00,x2=13.73).The incidence rate of pressure injury was 6.7％ in the experimental group,which was significantly lower than that (34.6％) in the control group (P=0.000,Z=-7.849).Conclusion There is high risk for pressure injury during long-distance referral of critical patients,and proper transport device has to be involved in to lower the risk effectively.

Explore the construction of thesaurus in the ancient literature of traditional Chinese medicine digital construction / 国际中医中药杂志

Chinese medical thesaurus was constructed setting knowledge element as the core and knowledge classification as the basis. In making the full use of our previous traditional knowledge classification research on traditional knowledge protection of TCM, the ancient literature of TCM knowledge classification system was constructed. The construction of TCM ancient books thesaurus plays a vital role in ancient Chinese medicine resource description, intelligent retrieval and knowledge discovery. This article disscussed the necessity of constructing Chinese medical thesaurus and the problems need to pay attention to in the process of building from three points of the Chinese medical thesaurus construction idea, plan, and the relevant system construction.

Correlates of bronchial asthma in Uygur and Han adults in Turpan prefecture, Xinjiang / 中华预防医学杂志

<p><b>OBJECTIVE</b>To analyze possible difference in bronchial asthma between ethnic and geographic groups and explore its correlates among Uygur and Han adults in Turpan Prefecture, Xinjiang.</p><p><b>METHODS</b>One hundred and sixty-six clinically diagnosed asthmatic patients at Turpan Prefecture Hospital, Xinjiang, 86 of Uygur and 80 of Han ethnic, and 166 1:1 matched controls from ophthalmological outpatient department at the same hospital were recruited into the study. Interview with questionnaire was conducted and serum levels of eosinophilic cation protein (S-ECP), total IgE (T-IgE) and specific IgE (S-IgE) were measured for all of the participants to study related factors for asthma with univariate and multivariate conditional logistic regression analyses.</p><p><b>RESULTS</b>Bronchial infection (OR(U) = 5.111, 95%CI: 1.203 - 21.710; OR(H) = 2.498, 95%CI: 1.471 - 5.069), family history of asthma (OR(U) = 3.078, 95%CI: 1.812 - 5.188; OR(H) = 2.711, 95%CI: 1.010 - 6.176), personal allergy history (OR(U) = 2.083, 95%CI: 1.043 - 4.162; OR(H) = 3.998, 95%CI: 1.739 - 9.198), weather change (OR(U) = 2.218, 95%CI: 1.199 - 3.778; OR(H) = 1.733, 95%CI: 1.004 - 2.994) and positive S-IgE (OR(U) = 1.592, 95%CI: 1.018 - 2.491; OR(H) = 3.858, 95%CI: 2.246 - 8.507) correlated with asthma in patients of both Uygur and Han ethnic. Percentage of asthma attack induced by respiratory infection [59.30% (51/86)] and weather change [36.05% (31/86)] in Uygur patients was significantly higher than that in Han ethnic [42.50% (34/80) and 21.25% (17/80), respectively], but percentage of those with personal allergy history [48.75% (39/80)] and positive S-IgE [52.50% (42/80)] in Han ethnic was significantly higher than that in Uygur [32.56% (28/86) and 30.23% (26/86), respectively]. Levels of S-ECP and T-IgE in patients with moderate and severe asthma of both Uygur and Han ethnic [(S-ECP(U) = 7.95 +/- 3.98) microg/L, S-ECP(H) = (11.21 +/- 4.74) microg/L, T- IgE(U) = (72.23 +/- 45.92) kU/L, T-IgE(H) = (108.81 +/- 64.07) kU/L, respectively]were significantly higher than those in controls of the same ethnic [S- ECP(U) = (1.94 +/- 1.16) microg/L, S-ECP(H) = (2.07 +/- 1.63) microg/L, T-IgE(U) = (46.19 +/- 32.47) kU/L, T-IgE(H) = (50.97 +/- 38.51) kU/L; t values were 8.96, 10.52, 2.81, 4.97, P < 0.01], higher in Han ethnic than those in Uygur (t values were 3.01, 2.68, P < 0.01).</p><p><b>CONCLUSION</b>Bronchial infection, family asthma history, personal allergy history, weather change and positive S-IgE all were important correlates of asthma in Turpan Prefecture, Xinjiang. Levels of S-ECP and T-IgE in patients with moderate and severe asthma increased during its attacks, higher in Han ethnic than those in Uygur. Genetic and environmental factors may be involved in occurrence and development of asthma.</p>

The regulation mechanisms of MMP-1,2 and TIMP-1,2 on wound healing after partial thickness scald / 中华外科杂志

<p><b>OBJECTIVE</b>To observe the changes of matrix metalloproteinase-1,2/tissue inhibitor of metalloproteinase-1,2 (MMP-1,2 and TIMP-1,2) in granulation tissue after 30% TBSA deeper partial thickness scald, and explore the regulation mechanism of MMP-2/TIMP-2 during wound healing.</p><p><b>METHODS</b>150 male Wistar rats were randomly divided into 5 groups as follows: (1) normal control (n = 6); (2) injured control group (n = 36): which is subdivided into postburn 3 h, 6 h, 1 d, 3 d, 7 d and 14 d groups, respectively; (3) BDM group (n = 36): intravenous injected of 400 mg 2,3-butanedione monoxime in each rat was done after anesthesia; (4) H7 group (n = 36): Each rat was intravenous injected of 0.2 mg 1-5-isoquinolinyl-sulfony-2-methylpiperazine after anesthesia; (5) anti-c-fos group (n = 36): Each rat was intravenous injected of 5 microg c-fos monoclony antibody after anesthesia. The immunohistochemistry staining technique and the reverse transcription polymerase chain reaction (RT-PCR) were used for detecting.</p><p><b>RESULTS</b>The expression of c-fos mRNA and protein was increased from 3 to 6 hours post-burn, and then decreased. The expression of MMP-1,2/TIMP-1,2 was delayed to 3 days post-burn compared with the expression of c-fos mRNA and protein. Treatment with BDM induced to raise c-fos mRNA and protein expression. The expression of MMP-1,2/TIMP-1,2 was also increased accordingly. However, following treatment with H7 inhibited the expression of c-fos mRNA and protein, MMP-1,2/TIMP-1,2 proteins expression decreased. Exogenous c-fos antibody could inhibit endogenous c-fos protein expression and the expression of MMP-1/TIMP-1,2 decreased, but MMP-2 has no notable changes.</p><p><b>CONCLUSIONS</b>The expression of MMP-1,2 and TIMP-1,2 has closely relation protein kinases activated signaling pathways. The expression changes of MMP-1 and TIMP-1/TIMP-2 depend on c-fos expression. Oncogenes play an important role in the change process of wound matrix degradation and remodeling.</p>

Effects of basic fibroblast growth factor on the matrix metalloproteinase-2,7 and its tissue inhibitor on deep partial thickness burn wounds in rats / 中华烧伤杂志

<p><b>OBJECTIVE</b>To observe the changes in matrix metalloproteinase-2,7 (MMP-2,7) and tissue inhibitor of metalloproteinase-2 (TIMP-2) in deep partial thickness burn during the process of wound healing, and the effects of bFGF on wound healing.</p><p><b>METHODS</b>The rats inflicted by 30% TBSA deep partial thickness burn were randomly divided into simple scald and bFGF treatment groups. Biopsies from wound skin were harvested at 3 and 6PBHs and 1, 3, 7, 14 PBDs for the detection of the epithelialization rate and collagen content. The above indices were also detected in the skin of another 6 normal rats as normal control.</p><p><b>RESULTS</b>(1) The epithelialization rate in bFGF treatment group was higher than that in simple scald group during 3PBH to 14 PBD. (2) The collagen contents in both bFGF treatment group and simple scald group were continually decreased during 3 PBH to 3 PBD, and increased from 7 to 14 PBD, but still lower than that in normal control (P < 0.05). (3) The expression of MMP-2,7 and TIMP-2 in simple scald group enhanced from 1 to 14 PBD, and peaked on 7 PBD. (4) The expression of MMP-2,7 in bFGF treatment group was similar to that in simple scald group from 3 to 6 PBH, while the expressions of MMP-2,7 and TIMP-2 was higher than those in simple scald group from 1 to 14 PBD.</p><p><b>CONCLUSION</b>The collagen deposition would be affected by the activities of extracellular matrix in scald wound in rats. Changes in MMP-2,7 and TIMP-2 expressions were an important process of wound repair, which was closely related to the acceleration of wound healing by the application of bFGF.</p>