ABSTRACT
For ancient period moon has been held responsible for many biological activities. That way, lunar cycle, by activity of moon, has been held responsible for increase in number of child birth. In this retrospective, observational study, we examined a total of 9890 full-term spontaneous deliveries as well as non-elective cesarean sections that occurred throughout 12 lunar months (February 7 th , 2008-January 25 th , 2009) in a rural medical college to evaluate the influence of the lunar position on the distribution of deliveries among Indian population. Student's 't' test and ANOVA were used for statistical analysis where each delivery was considered as a single measure. We found no significant differences in the frequency of births during various phase of lunar cycle regardless of route of delivery. Our observations do not support the hypothesis of a relationship between lunar cycle and the frequency of obstetric deliveries.
ABSTRACT
Circumscribed choroidal hemangiomas are rare ophthalmic entities that cause diminution in vision due to accumulation of subretinal and/or intraretinal fluid in the macular area. Various treatment options ranging from conventional laser to photodynamic therapy have been employed to destroy the tumor and reduce the exudation; however, either the inability to penetrate through the exudative fluid or the collateral retinal damage induced by these treatment modalities make them unsuitable for lesions within the macula. We evaluated the role of intravitreal bevacizumab, a pan-vascular endothelial growth factor (VEGF) inhibitor, in reducing the sub- and intraretinal fluid in three patients with circumscribed choroidal hemangiomas. All the patients had complete resolution of the serous retinal detachment that was maintained till at least 12 months after the first injection. Intravitreal bevacizumab may be used in combination with thermal laser or photodynamic therapy in treating circumscribed choroidal hemangiomas with subretinal fluid.
Subject(s)
Adult , Antibodies, Monoclonal/administration & dosage , Antibodies, Monoclonal, Humanized , Body Fluids/drug effects , Body Fluids/metabolism , Choroid Neoplasms/complications , Choroid Neoplasms/diagnosis , Choroid Neoplasms/drug therapy , Drug Administration Schedule , Eyeglasses , Fluorescein Angiography , Hemangioma/complications , Hemangioma/diagnosis , Hemangioma/drug therapy , Humans , Intravitreal Injections , Male , Retina/drug effects , Retina/metabolism , Retinal Detachment/drug therapy , Retinal Detachment/etiology , Tomography, Optical Coherence , Vascular Endothelial Growth Factor A/antagonists & inhibitors , Visual AcuityABSTRACT
Sympathetic ophthalmia following parsplana vitrectomy is a known complication. We describe here a case of recurrent disc neovascularization in a patient of sympathetic ophthalmia. It promptly responded to steroids initially but later recurred with inflammation.
Subject(s)
Adult , Combined Modality Therapy , Female , Fluorescein Angiography , Glucocorticoids/therapeutic use , Humans , Laser Coagulation , Methotrexate/therapeutic use , Ophthalmia, Sympathetic/complications , Optic Disk/blood supply , Recurrence , Retinal Neovascularization/diagnosis , Triamcinolone Acetonide/therapeutic use , Visual AcuityABSTRACT
The methanol extract of the leaves of E. adenophorum (100, 200 and 300 mg/kg, po) showed significant analgesic activity, as compared to standard drugs diclofenac sodium and pentazocine, employing acetic acid-induced writhing test, tail immersion test and tail flick test models.