ABSTRACT
Objective: The aim was to assess the peri-implant clinical and radiographic parameters and whole salivary levels of interleukin [IL]-1Beta and IL-6 among type 2 diabetic and nondiabetic patients with and without peri-implantitis
Material and Methods: Ninety-one implants were placed in patients without type 2 diabetes mellitus [39 patients with and 52 patients without peri-implantitis; group 1]. Eighty implants were placed in patients with diabetes [35 patients with and 45 patients without peri-implantitis; group 2]. Peri-implant plaque index, bleeding on probing, probing depth, and marginal bone loss were measured. Unstimulated whole saliva samples were collected and IL-1Beta and IL-6 levels were measured using standard techniques. p < 0.05 was considered statistically significant
Results: In group 1, plaque index [p < 0.001], bleeding on probing [p < 0.001], probing depth [p < 0.001], and whole salivary IL-1Beta [p < 0.001] and IL-6 [p < 0.001] levels were significantly higher in patients with peri-implantitis than in those without peri-implantitis. Plaque index, bleeding on probing, probing depth, and marginal bone loss were comparable among all of the patients in group 2. Among patients with peri-implantitis, plaque index [p < 0.001], bleeding on probing [p < 0.001], probing depth [p < 0.001], marginal bone loss [p < 0.001], and whole salivary IL-1â [p < 0.001] and IL-6 [p < 0.001] levels were significantly higher in those with diabetes than in those without diabetes
Conclusion: Among individuals without diabetes, peri-implant plaque index, bleeding on probing, probing depth, marginal bone loss, and whole salivary IL-1 Beta and IL-6 levels were higher among patients with peri-implantitis compared to patients without peri-implantitis. Among patients with diabetes, the severity of the measured parameters appears to be influenced by the glycemic status rather than by peri-implantitis
ABSTRACT
Severe periodontal inflammation with generalized dental plaque accumulation, spontaneous and severe gingival bleeding, fungal infection, and interdental papillae necrosis are presented in a patient infected with human immunodeficiency virus [HIV]. Bite-wing radiographs revealed a generalized horizontal alveolar bone loss of 7-8 millimetres in both arches. Erythematous patches were noted on the gingival mucosa in both jaws. DNA testing was performed to indentify the periodontopathogens. The patient had no signs or symptoms of acquired immunodeficiency syndrome. This case-report presents the massive periodontal destruction that occurred in a patient infected with HIV. Therefore, it is highly recommended that patients infected with HIV should be regularly monitored to aid in early detection and to provide proper management of periodontal inflammatory conditions to minimize its destruction
ABSTRACT
Periodontal regenerative techniques have been proposed; however, the outcomes remain debatable. The present investigation assessed the regenerated cementum following enamel matrix derivative application in dehiscence-type defects. Buccal osseous dehiscences were surgically created on the maxillary cuspid, and the second and fourth premolars in five female beagle dogs. The treatment group (n = 15 sites) received the enamel matrix derived application, whereas the control groups (n = 15) did not. The dogs were sacrificed 4 months following treatment and the specimens were histologically and histometrically examined. The newly formed cementum was uneven in thickness and mineralization, overlapped the old cementum and exhibited functional orientation, cementocyte lacunae and collagen fibril bundles. Most of the histological specimens showed the presence of a gap between the newly formed cementum and the underlying dentin. Control sites did not exhibit any cementum formation. The present study concluded that newly formed cementum is of cellular type and exhibits multiple characteristics.