ABSTRACT
Objective: The molecularly imprinted osthole on surface-modified quartz sand was prepared and characterized by SEM and FT-IR. The adsorption properties of molecularly imprinted materials were investigated. Methods: The morphology of MIP was prepared using N-(β-aminoethyl)-γ-aminopropylmethylbimethoxy silane (KH-602) modified quartz sand as supporter, osthole as template, methacrylic acid (MAA) as functional monomer, ethylene glycol dimethacrylate (EGDMA) as crosslinker, axodiisobutyronitrile (AIBN) as initiator, and methanol as porogen, observed by SEM, and the chemical structure of MIP was characterized by FT-IR. Results: The dynamic adsorption experiment showed that the adsorption capacity of molecularly imprinted materials to osthole gradually reached saturation with the increase of time. The maximum adsorption capacity of molecularly imprinted materials for osthole was studied by static adsorption experiment. The selective adsorption experiment was adopted to study the binding properties and molecule recognition characters of molecularly imprinted materials for osthole. Conclusion: The experimental results showed that MIP had specific recognition selectivity, excellent binding affinity and elution property for ractopamine. The MIP on the adsorption ability of osthole was significantly better than xanthotoxin and imperatorin.