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Journal of Dentistry-Shiraz University of Medical Sciences. 2018; 19 (3): 212-216
in English | IMEMR | ID: emr-199512

ABSTRACT

Statement of the Problem: Lichen planus disease is a chronic inflammatory lesion without a known etiology. Recent studies have indicated the role of vitamin D on immune system and proposed its anti-inflammatory effects


Purpose: This study aimed to compare vitamin D serum levels in patients with oral lichen planus and healthy subjects


Materials and Method: In this case.control study, 18 patients suffering from oral lichen planus referred to the Department of Oral Medicine, Tabriz Faculty of Den-tistry were chosen as the case group and 18 healthy people were chosen as the con-trol group. A 5-mL blood sample was taken from all subjects and the subjects' vitamin D serum levels were assessed with a vitamin D total [25-hydroxy vitamin D] kit by employing the electrochemiluminescence technique. The results were analyzed and compared by using SPSS17 statistic software. p< 0.05 was considered statistically significant


Results: The mean vitamin D level in serum of patients with oral lichen planus was 30.7+/- 20.38ng/ml and in healthy subjects was 36.45 +/- 15.33ng/ml, the difference was not statistically significant [p= 0.346]


Conclusion: The difference between the level of vitamin D in the serum of patients suffering from oral lichen planus and healthy individuals was not significant

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