ABSTRACT
Introduction: malignant Lymphoma is a primary neoplasm of lymphoid tissue. It is the third most common cancer in children worldwide. There are.two broad categories of malignant Lymphoma: Non-Hodgkin's lymphoma and Ihdgkin's disease with different microscopic features, treatment, and prognosis
Aim of the work: to determine the types of lymphoma in all ages, and in relation to gender and site of lymph node involvement in Hadhramout governorate
Materials and methods: this is a retrospective descriptive study of 170 cases of lymphomas retrieved from the archives of National Oncology Center, Hadhramout during the period between 2008-2013. The diagnosis was assessed by immunohistochemical results and categorized according to WHO classification of lymphoid neoplasms
Results: Out of 170 cases, [116/170, 68.2%] had Non-Hodgkin's lymphoma and [54/170, 31.8%] had Hodgkin's Iymphoma. A male predominance was observed [103/170, 60.6%]. B cell lymphomas were the most frequent Non-Hodgkin's lymphoma type [95/116, 81.9%] and diffuse large B-cell lymphoma was the common pattern of Non-Hodgkin's lymphoma [58/95, 61.1%] of all Non- Hodgkin's lymphomas] followed by the Burkitt's lymphoma [20/95, 21.1%]+ The distribution of Hodgkin's lymphoma showed predominance of nodular sclerosis classical Hodgkin's lymphoma [38/54, 70.4%] of all Hodgkin's Iymphoma]. The proportion of lymph node [nodal] involvement of lymphomas is higher than extra-nodal, being seen in [91/116, 78.5%] of all Non-Hodgkin's lymphoma and [49/54,90.8%] of all Hodgkin's lymphoma
Conclusion: Non-Hodgkin's lymphoma is the most common type of malignant lymphoma, and DLBCL is the most common type, while nodular sclerosis classical Hodgkin's lymphoma is the most common type of Hodgkin's lymphoma. The nodal involvement of malignant lymphoma is higher than extra-nodal
ABSTRACT
Introduction: Dysfunctional uterine bleeding is one of the most common causes for the gynecological patients. This was a retrospective study of different patterns of endometrial pathology and to correlate the histopathology of endometrium with clinical parameters
Material and Methods: This reterospective study was carried out on 215 females over the age of 20 years with DUB at our laoratory sent by gynecologist from Universal Hospital and Al-Amal private clinic, during October 2011 to September 2013
Results: the most common age group presenting of DUB was in age group of 40-49 years [40.50%]. DUB was most frequently seen in grand multipara [75.8%]. Menorrhagia was the predominant bleeding pattern [43.7%]. The normal physiological endometrium [proliferative and secretory endometrium] was the commonest endometrial histopathological diagnosis [51.1%], followed by endometrial hyperplasia [26%]. There were statistically significant relationship between the parity and the bleeding patterns and between endometrial histopathological diagnosis and the parity age and the patterns of bleeding [P value<0.05]
Conclusion: DUB predominantly affects women of 40-49 years old. DUB is common in grand multiparous women and menorrhagia is the most common presenting bleeding pattern. Proliferative and secretory endometrium followed by endometrial hyperplasia is the major endometrial histopathological findings. The parity is significant correlated with bleeding patterns and endometrial histopathological diagnosis; grand multiparous women can be presented with any patterns of bleeding mainly menorrhagia with endometrial hyperplasia. The endometrial histopathological diagnosis was significantly related to age, the majority of endometrial hyperplasia are in age >/= 50 years