ABSTRACT
Hypertension is one of the major risk factor for cardiovascular morbidity and mortality. One of primary management of hypertension include dietary changes which could incorporate dietary supplementation ,also use of non pharmacological treatment options is high in patients with high blood pressure .Garlic has played an important dietary as well as medicinal role in human history and it has been on the top ten lists of herbal sales among people. For evaluating the effect of garlic on blood pressure ,we reviewed clinical trials published from 1982 until 2013 by searching in informative bank such as PubMed ¡Ovid ¡ Elsevier Science , Google Scholar with keywords garlic , blood pressure, hypertension and herbal supplement. The result of this review article showed that several clinical trials have suggested garlic lowers systolic and or diastolic blood pressure and has beneficial effect in controlling hypertension, but negative results also have been obtained in some of trials .Blood pressure reducing properties of garlic have been linked to its hydrogen sulphide production and allicin content , liberated from alliin and the enzyme alliinase. large scale trials are needed to investigate whether standardized garlic preparations could provide a safe alternative or complementary treatment option for hypertension in clinical practice
ABSTRACT
Osteoporosis is one of the health problems that affect lives of many people. This study was designed to assess nutritional intake and dietary habit in osteoporotic patients. The population of this analytical cross-sectional study was 120 osteoporotic patients with 45-89 years old referred to rheumatologic clinic of Tabriz .Nutritional intake and dietary habit was determined by 3 day food recall and food frequency questionnaire¡ individual and clinical information by questionnaire and weight and height of subjects were measured by scale. Results of this study found that mean age of patients were 57.10 years old. The mean T-score of patients was -3.31+/-0.07SD.Analysis of FFQ questionnaire showed that dietary habit and food choice in osteoporotic patients was not suitable. Mean intake of zinc, calcium and vitamin D in patients was significantly lower than normal value [p<0.05]and intake of protein ,iron and phosphor was higher than normal range. With notice the vital role of nutrition and dietary intake on bone mass, nutritional education and training in osteoporotic patients beside supplementation is suggested
ABSTRACT
Studies have demonstrated that zinc plays an important role in development of cardiovascular diseases in Western populations. But there is little data for other racial groups. This study was aimed to investigate the association between serum zinc and coronary artery disease [CAD] in Iranian subjects.This study was conducted on 81 subjects, which referred to Heshmat Hospital of Guilan province, Iran, for routine coronary angiography from June to August 2011. Subjects were assigned into 2 groups; 41 CAD patients. case and 40 healthy subjects in control group. Data about smoking habit,physical activity, dietary intake and anthropometric indices were collected by questionnaire. Serum zinc was measured by atomic spectroscopy. The serum zinc concentrations were significantly lower in case group than control [p<0.05]. The mean serum zinc concentration in the case and control group was 73.50 +/- 1.61microg/dl and 78.47 +/- 1.66 micro g/dl, respectively. subjects that lives in rural area had 7.11-fold higher CAD risk in compare to subjects lives in urban after adjustment for confounder factors, they also had lower zinc concentration than urban [p<0.05]. in our study With increasing in serum zinc concentration CAD risk decrease 0.94-fold.Zinc concentration had significant correlation with age [r= -0.23 p<0.05], weight [r=0.26 p<0.05] and Place for living [r=- 0.22 p= 0.04].There were no significant correlation between the dietary intake, Waist circumference ,smoking and serum zinc concentration in our study. Serum zinc concentration was significantly lower in the north of Islamic Republic of Iran patients with abnormal versus those with a normal angiogram. It seems Serum zinc concentration correlate with some risk factors for coronary artery disease
ABSTRACT
Research on the zinc status of osteoporotic women is scarce. This randomized, double-blind, placebo controlled clinical trial assessed the effect of zinc supplementation on serum zinc and calcium levels in postmenopausal osteoporotic women. A sample of 60 women referred to a rheumatology clinic in Tabriz were randomly divided into intervention [220 mg zinc sulfate daily] and placebo groups. Anthropometric indices, dietary intake of zinc and calcium and serum zinc and calcium were assessed at baseline and after 60 days. Mean serum zinc concentrations were markedly lower than the normal range at baseline, but mean serum calcium levels were normal. In the intervention group serum zinc levels were significantly higher after 60 days [120.5 [SD 7.5] versus 70.5 [SD 4.6] microg/dL] while serum calcium levels were unchanged [8.6 [SD 0.1] versus 9.1 [SD 0.3] mg/dL]. The placebo group showed no significant changes in zinc or calcium levels. Postmenopausal osteoporotic women may benefit from zinc supplementation