ABSTRACT
A pandemia da doença por coronavírus (COVID-19), teve seus primeiros casos localizados em Wuhan, na China, em dezembro de 2019. Por ser considerada infecciosa e altamente contagiosa causando problemas respiratórias, levou à inúmeras mudanças no calendário letivo das instituições de ensino. O presente estudo tem como objetivos rastrear o perfil dos acadêmicos de Fisioterapia reconhecendo os impactos da pandemia em sua saúde geral, bem como examinar as maiores dificuldades acadêmicas durante esse período. Trata-se de um levantamento de dados de caráter qualitativo, cuja fonte foi o Centro Universitário São Camilo (CUSC) durante os meses de agosto, setembro e outubro de 2021, totalizando 169 respostas. Foi observado que durante a pandemia, 45 (26,6%) dos estudantes apresentaram algum problema de saúde. Quanto às atividades diárias, 111 (65,7%) afirmaram que conseguiram adaptar atividades de lazer em casa, 84 (49,7%) tiveram seus hábitos alimentares piorados e 57 (33,7%) afirmaram ter menos de oito horas de sono. Em relação ao ensino à distância, 68 (40,2%) consideraram seu rendimento acadêmico regular e 156 (92,3%) se sentiram prejudicados de alguma forma. Além disso, 111 (65,7%) consideraram o ensino remoto extremamente estressante, onde a maioria optou pelo retorno presencial, sendo que 77 (45,6%) gostariam de retomar as atividades presenciais de forma completa e 76 (45,0%) optaram pelo retorno gradual. Foi constatado que o perfil dos acadêmicos de fisioterapia do CUSC passou por mudanças significativas em diversos aspectos, como sono, alimentação e principalmente referente à questões psicológicas e acadêmicas, havendo pontos positivos e negativos dessa forma de ensino.
The first case of the coronavirus disease (COVID-19) pandemic was located in Wuhan, China, in December 2019. As it is considered infectious and highly contagious, causing respiratory problems, it has led to numerous changes in the academic calendar of educational institutions. The present study aims to track the profile of physiotherapy students, recognizing the impacts of the pandemic on their overall health, as well as examining the greatest academic difficulties during this period. This is a qualitative data survey, collected from Centro Universitário São Camilo (CUSC) students during the months of August, September, and October 2021, totaling 169 responses. It was observed that during the pandemic, 45 (26.6%) students had some health problems. As for daily activities, 111 (65.7%) stated that they managed to adapt leisure activities at home, 84 (49.7%) worsened their eating habits, and 57 (33.7%) stated that they had less than eight hours of sleep. Regarding online learning, 68 (40.2%) considered their academic performance regular and 156 (92.3%) felt impaired in some way. In addition, 111 (65.7%) considered remote learning extremely stressful, where the majority opted for in-person classes, with 77 (45.6%) wanting to resume in-person activities completely, and 76 (45.0%) opted for a gradual return. It was found that the profile of CUSC physiotherapy students underwent significant changes in several aspects, such as sleep and diet, but mainly psychological and academic issues were referred to, with positive and negative points concerning online learning.
ABSTRACT
Abstract INTRODUCTION: Although supervised doses are essential for reducing leprosy treatment failure, the impact of specific drug interactions has rarely been assessed. This study aimed to estimate the risk of leprosy treatment suspension in patients receiving polypharmacy. METHODS We performed this case-control study in which the primary outcome was defined as the need to discontinue multibacillary leprosy treatment for at least one supervised dose, and the main risk factor was the detection of polypharmacy. Multivariate analysis by logistic regression was used for calculating odds ratio (OR). RESULTS: This study included 103 patients, of whom 43 needed to discontinue leprosy treatment (hemolysis = 26, hepatitis = 2, hemolysis associated with hepatitis = 6, and suspected treatment resistance = 9) and the rest did not. The severity of drug interactions had no effect on treatment discontinuation. Patients who used five or more drugs in addition to leprosy treatment had almost a 4-fold greater risk of treatment suspension (OR, 3.88; 95% confidence interval: 1.79-9.12; p < 0.001). The number of drugs used also positively influenced the occurrence of hemolysis (p < 0.001). No patient presented evidence of molecular resistance to rifampicin, dapsone, or ofloxacin treatment, as evidenced by genetic sequencing detection of rpoB, folp1, and gyrA mutations. CONCLUSIONS: Polypharmacy has deleterious effects on the already difficult-to-adhere-to treatment of leprosy and polypharmacy induces hemolysis. Additional measures must be taken to avoid the undesirable effects of inadequate polypharmacy.