ABSTRACT
Reliability and validity of health assessment questioner have been shown for rheumatoid arthritis but not osteoarthritis in Iranian patients. Having an instrument for measuring of pain and disability is needed for evaluation of patients and disease course in studies. So this study was designed for evaluating of validity and reliability of Persian HAQ in osteoarthritis. From 177 patients with hand and/or knee osteoarthritis, 100 patients were chosen according HADS score equal or less than 7. Short Form of Health Survey [SF-36], pain and disability according Visual analogue scale [VAS] and Persian version of Health assessment questioner [HAQ] were completed. HAQ was re-evaluated after one week. Correlation between Persian HAQ, SF 36 and VAS and test-retest reliability were evaluated by Spearman correlation coefficient and Cronbach's alpha coefficient. Correlation coefficient for HAQ 1 and VAS for pain was [r=0.75, p=0.001] and for SF 36 was [r=0.70, p=0.001]. Correlation coefficient for HAQ 1 and HAQ 2 was 0.93 for hand OA, 0.96 for knee OA and 0.94 for all patients [r= 0.92, p=0.001]. HAQ had a good internal consistency in osteoarthritis [Cronbach's alpha coefficient=0.87]. Criterion and structure validity used in study. This study has shown good validity reliability for persian HAQ in Iranian patients with osteoarthritis
ABSTRACT
The association of Takayasu arteritis [TA] and inflammatory bowel disease is rare. Early diagnosis and treatment many influence patient survival. This report describes a 35-year-old woman who had been treated for ulcerative colitis [UC] that manifested with weight loss, upper limb cluadication and vertigo. The diagnosis of TA was made according to the American College of Rheumatology criteria. The patient received corticosteroids and cyclophosphamide; however she experienced two additional cerebral events and died after four months. Although the association of TA with UC is rare, we recommend it be considered in young patients with UC who suffer from unexplained weight loss and other constitutional symptoms or cerebrovascular accidents
Subject(s)
Humans , Female , Colitis, Ulcerative , Weight Loss , Early Diagnosis , Inflammatory Bowel DiseasesABSTRACT
Heterotopic Ossification is bone formation outside the skeletal system. Endosulfan is a pesticide in organochlorines family and endosulfan poisoning can make neurologic toxicity with loss of consciousness, diffuse convulsion and status epilepticus. There are some reports about heterotopic ossification due to neurologic and poisoning events, but there is not any report of it after endosulfan poisoning in the literature. A 44 year old man, presented with pelvic pain and difficulties in walking. There was a history of status epilepticus and coma 4 months ago due to endosulfan poisoning. There was some heterotopic bone formation around hip joints in radiography. Because of high mortality and morbidity due to endusolfan toxicity and absence of any antidote, it is recommended that its availability be restricted and its toxicity be treated immediately specially for convulsion