ABSTRACT
BACKGROUND@#Arsenic and heavy metals are the main cause of water pollution and impact human health worldwide. Therefore, this study aims to assess the probable health risk (non-carcinogenic and carcinogenic risk) for adults and children that are exposed to arsenic and toxic heavy metals (Pb, Ni, Cr, and Hg) through ingestion and dermal contact with drinking water.@*METHOD@#In this study, chemical analysis and testing were conducted on 140 water samples taken from treated drinking water in Mashhad, Iran. The health risk assessments were evaluated using hazard quotient (HQ), hazard index (HI), and lifetime cancer risk (CR).@*RESULTS@#The results of the HQ values of arsenic and heavy metals for combined pathways were below the safety level (HQ < 1) for adults, while the HI for children were higher than the safety limit in some stations. Likewise, Cr showed the highest average contribution of HI (55 to 71.2%) for adult and children population. The average values of total carcinogenic risk (TCR) through exposure to drinking water for children and adults were 1.33 × 10 and 7.38 × 10, respectively.@*CONCLUSION@#Overall, the CR through exposure to drinking water for children and adults was borderline or higher than the safety level of US EPA risk, suggesting the probability of carcinogenic risk for the children and adults to the carcinogenic elements via ingestion and dermal routes. Therefore, appropriate purification improvement programs and control measures should be implemented to protect the health of the residents in this metropolitan city.
ABSTRACT
Background: Diabetes is a chronic metabolic disorder that leads to some of complications such as nerve damage that decrease proprioception sense and balance and cause cardiovascular disease. Physical activity is very important in daily schedule and improves sensitivity to insulin. The aim of this study was to investigate the effect of of 8 weeks of selective physical activity on static balance and aerobic capacity in female patients with type 2 diabetes.
Material and Methods: This quasi-experimental study was carried out on 17 women with type 2 diabetes. The subjects selected according to investigation items and accessible sampling method. They were assigned in two experimental [age=51.4 +/- 7.3, n=8] and control [age=55.7 +/- 4.9, n=9] groups. Experimental group underwent three sessions of one hour selected exercise per week for 8 weeks. Control group did not participate in any regular exercise sessions. Static balance assess with stroke stand test and aerobic capacity measured with 6 min walk test for all subjects. Data were analyzed by SPSS 16.0 software and ANCOVA [p
Findings: There was no significant difference between mean of balance time between pre-test and post-test in experimental group than control group [P
Conclusion: A period of physical activity could increase aerobic capacity in type 2 diabetic patients and don't have significant influence on static balance.