ABSTRACT
Background: The Lamiaceae family has been tried to ameliorate symptoms of stomachache and dysmenorrheal in traditional medicine. The extracts and essential oils obtained from these plants have recently attracted much scientific attention. The essential oils of some plants belonging to this family have also been used in food preservation
Methods: This study employed pharmaco-diagnostic methods to examine and compare the antioxidant and antibacterial activities of the essential oils obtained from two Iranian plants Zhumeria majdae and Salvia mirzayanii in E.coli infection
Results: Our findings suggested that the essential oil extracted from S. mirzayanii had more antioxidant potential than Z. majdae. By increasing the concentration of both agents, the growth and specific growth activity of E. coli was reduced. At 1:200 dilutions, the growth of E. coli was inhibited while LC50 occurred at 1:1000 dilutions. Finally, our results showed that both agents had strong antioxidant and antibacterial activities with more significant properties favoring S. mirzayanii
Conclusion: Plants such as Z. majdae and S. mirzayanii retain notable medicinal properties and may serve as useful tools when developing natural antibiotics and antioxidant agents against common pathogens including E. coli