ABSTRACT
Compared with normal mice, the concentration of serum zinc in zinc-deficient mice was significantly increased after oral administration of 1m<i>l</i> of 1000ppm ZnSO<sub>4</sub> solution, while that of zinc-deficient mice treated with Kampo (Pogostemi Folium et Rhizoma, Perilla Herba, Saussureae Radix, Aurantii Nobilis Pericarpium, Anemarrhena Rhizoma, etc.) was not increased. The intestinal mucosa of zinc-deficient mice was also remarkably injured with administration of ZnSO<sub>4</sub> but the Kampo formula inhibited its injury.
ABSTRACT
The Chinese herbal medicine (_??__??_, _??__??_, _??__??_, _??__??_, _??__??_, _??__??__??_) suppressed the injury of intestinal mucosa in mice with excess zinc administrations. The increase of serum zinc concentration with excess zinc administrations was also inhibited by administrations of the Chinese herbal medicine.
ABSTRACT
The injury of intestinal mucosa of mice with zinc-deficiency was inhibited by the Chinese herbal medicine (_??__??_, _??__??_, _??__??_, _??__??_, _??__??_, _??__??__??_), while the concentration of serum zinc in zinc deficient mice was not increased after administrations of the Chinese herbal medicine.